Side effects suspected to be related to doxycycline use in cats

Doxycycline-hyclate and doxycycline-hydrochloride are causing acidic solutions with a pH of 2.0-3.0, while doxycycline-monohydrate forms a solution with a pH around 5.0-6.5 ( Bokey and Hugh 1975 , Carlborg and Farmer 1983 ). [...]doxycycline-hyclate and doxycycline-hydrochloride are thought to conta...

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Bibliographic Details
Published in:Veterinary record 2013-02, Vol.172 (7), p.184-184
Main Authors: Schulz, B. S., Zauscher, S., Ammer, H., Sauter-Louis, C., Hartmann, K.
Format: Article
Language:English
Subjects:
Alanine Transaminase - drug effects
Alkaline Phosphatase - drug effects
Animals
Anorexia
Anti-Bacterial Agents - adverse effects
Bacterial infections
Cat Diseases - chemically induced
Cats
Diarrhea
Doxycycline - adverse effects
Drug dosages
Enzymes
Female
Gastrointestinal Diseases - chemically induced
Gastrointestinal Diseases - veterinary
Laboratory animals
Liver
Male
Retrospective Studies
Studies
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Summary:Doxycycline-hyclate and doxycycline-hydrochloride are causing acidic solutions with a pH of 2.0-3.0, while doxycycline-monohydrate forms a solution with a pH around 5.0-6.5 ( Bokey and Hugh 1975 , Carlborg and Farmer 1983 ). [...]doxycycline-hyclate and doxycycline-hydrochloride are thought to contain a higher potential for gastrointestinal irritation. [...]it seems advisable to avoid subcutaneous or intravenous injections of doxycycline in cats, if possible.
ISSN:0042-4900
2042-7670
DOI:10.1136/vr.101031