Cyclic alternating pattern analysis in REM sleep behavior disorder

• Published in: Sleep & breathing 2013-03, Vol.17 (1), p.209-215
• Main Authors: Kutlu, Ayşe, İşeri, Pervin, Selekler, Macit, Benbir, Gülçin, Karadeniz, Derya
• Format: Article
• Language: English
• Subjects: Aged; Arousal - physiology; Biological and medical sciences; Cerebral Cortex - physiopathology; Dentistry; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes; Electroencephalography; Eye movements; Female; Fundamental and applied biological sciences. Psychology; Humans; Internal Medicine; Male; Medical sciences; Medicine; Medicine & Public Health; Middle Aged; Motor ability; Nervous system (semeiology, syndromes); Nervous system as a whole; Neurology; Original Article; Otorhinolaryngology; Pediatrics; Pneumology/Respiratory System; Polysomnography; REM Sleep Behavior Disorder - diagnosis; REM Sleep Behavior Disorder - physiopathology; Signal Processing, Computer-Assisted; Sleep apnea; Sleep Stages - physiology; Sleep. Vigilance; Statistics as Topic; Vertebrates: nervous system and sense organs
• ISSN: 1520-9512; 1522-1709
• DOI: 10.1007/s11325-012-0675-5

Objective Rapid eye movement (REM) sleep behavior disorder (RBD) is a type of REM parasomnia characterized by complex motor activity during REM sleep. In this study, cyclic alternating pattern (CAP) in patients with idiopathic RBD was analyzed to evaluate the expression of arousal instability of NREM sleep. Methods A total of 31 idiopathic RBD patients and age- and gender-matched 21 control subjects were consecutively recruited. Conventional sleep polysomnographic recording parameters and CAP parameters were compared between RBD and the control group. Results The number of CAP cycles (120.13 ± 113.56, p  = 0.007), CAP sequences (20.9 ± 18.15, p