Is Gender a Factor in the Reduction of Cardiovascular Risks With Exercise Training?

Background: This study compared older men and women with cardiovascular (CV) risk factors in terms of the effects of a 6-month exercise intervention on high-sensitivity C-reactive protein (hsCRP) levels, blood pressure (BP) and other risk factors. Methods and Results: Sixty older (age 61–79) overwei...

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Published in:Circulation Journal 2013, Vol.77(3), pp.646-651
Main Authors: Morita, Noriteru, Okita, Koichi
Format: Article
Language:English
Subjects:
Aged
Aortic diseases
Blood Glucose - metabolism
Blood Pressure - physiology
Body Weight - physiology
C-Reactive Protein - metabolism
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - metabolism
Cardiovascular Diseases - prevention & control
Cholesterol - blood
Exercise - physiology
Female
Humans
Hypertension
Male
Metabolic syndrome
Middle Aged
Physical fitness
Resistance Training
Risk Factors
Sex characteristics
Sex Factors
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creator Morita, Noriteru
Okita, Koichi
description Background: This study compared older men and women with cardiovascular (CV) risk factors in terms of the effects of a 6-month exercise intervention on high-sensitivity C-reactive protein (hsCRP) levels, blood pressure (BP) and other risk factors. Methods and Results: Sixty older (age 61–79) overweight men and 71 such women with 2 or more risk factors (ie, systolic BP 130–179mmHg, non-fasting blood glucose 110–139mg/dl, and low-density lipoprotein cholesterol 120–219mg/dl) participated in a 6-month exercise intervention. The exercise program consisted of moderate-intensity bicycle exercise for ∼40min, performed on average 2.5 times per week. Systolic and diastolic BP reductions were found to be greater in women than in men (SBP, −10.6 vs. −5.5mmHg; DBP, −6.2 vs. −3.3mmHg; both P
doi_str_mv 10.1253/circj.CJ-12-0607
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Methods and Results: Sixty older (age 61–79) overweight men and 71 such women with 2 or more risk factors (ie, systolic BP 130–179mmHg, non-fasting blood glucose 110–139mg/dl, and low-density lipoprotein cholesterol 120–219mg/dl) participated in a 6-month exercise intervention. The exercise program consisted of moderate-intensity bicycle exercise for ∼40min, performed on average 2.5 times per week. Systolic and diastolic BP reductions were found to be greater in women than in men (SBP, −10.6 vs. −5.5mmHg; DBP, −6.2 vs. −3.3mmHg; both P&lt;0.05). Decreases in body mass index were larger in women than in men (P&lt;0.05). There was no significant gender difference in the changes in blood glucose and lipid profiles and hsCRP levels. After adjustment for confounders (exercise frequency, weight loss, age, and baseline values), there were still significant gender differences in the SBP and DBP reductions. hsCRP reduction were similar in both genders even after adjusting for weight loss. 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Methods and Results: Sixty older (age 61–79) overweight men and 71 such women with 2 or more risk factors (ie, systolic BP 130–179mmHg, non-fasting blood glucose 110–139mg/dl, and low-density lipoprotein cholesterol 120–219mg/dl) participated in a 6-month exercise intervention. The exercise program consisted of moderate-intensity bicycle exercise for ∼40min, performed on average 2.5 times per week. Systolic and diastolic BP reductions were found to be greater in women than in men (SBP, −10.6 vs. −5.5mmHg; DBP, −6.2 vs. −3.3mmHg; both P&lt;0.05). Decreases in body mass index were larger in women than in men (P&lt;0.05). There was no significant gender difference in the changes in blood glucose and lipid profiles and hsCRP levels. After adjustment for confounders (exercise frequency, weight loss, age, and baseline values), there were still significant gender differences in the SBP and DBP reductions. hsCRP reduction were similar in both genders even after adjusting for weight loss. 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subjects Aged
Aortic diseases
Blood Glucose - metabolism
Blood Pressure - physiology
Body Weight - physiology
C-Reactive Protein - metabolism
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - metabolism
Cardiovascular Diseases - prevention & control
Cholesterol - blood
Exercise - physiology
Female
Humans
Hypertension
Male
Metabolic syndrome
Middle Aged
Physical fitness
Resistance Training
Risk Factors
Sex characteristics
Sex Factors
title Is Gender a Factor in the Reduction of Cardiovascular Risks With Exercise Training?
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