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Long-term bladder function, fertility and sexual function in patients with posterior urethral valves treated in infancy
Abstract Objective To address the issue of sexual function and fertility in PUV patients. Patients and methods Of 47 patients (age > 18 years) treated for PUV in infancy 28 were contactable. They were sent a standard questionnaire requesting details on voiding dysfunction symptoms, and experience...
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| Published in: | Journal of pediatric urology 2013-02, Vol.9 (1), p.38-41 |
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| container_title | Journal of pediatric urology |
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| creator | López Pereira, P Miguel, M Martínez Urrutia, M.J Moreno, J.A Marcos, M Lobato, R Jaureguízar, E |
| description | Abstract Objective To address the issue of sexual function and fertility in PUV patients. Patients and methods Of 47 patients (age > 18 years) treated for PUV in infancy 28 were contactable. They were sent a standard questionnaire requesting details on voiding dysfunction symptoms, and experience of erection, orgasm and ejaculation. Results Of the 28, 16 (mean age 24 years) returned the questionnaire. Voiding frequency ranged from 3 to 10 times per day (mean = 5). Two patients had occasional mild diurnal incontinence but none had symptoms of overactivity. Three patients had a weak urinary stream. Renal function was normal in 9, 4 had a glomerular filtration rate |
| doi_str_mv | 10.1016/j.jpurol.2011.11.006 |
| format | article |
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Patients and methods Of 47 patients (age > 18 years) treated for PUV in infancy 28 were contactable. They were sent a standard questionnaire requesting details on voiding dysfunction symptoms, and experience of erection, orgasm and ejaculation. Results Of the 28, 16 (mean age 24 years) returned the questionnaire. Voiding frequency ranged from 3 to 10 times per day (mean = 5). Two patients had occasional mild diurnal incontinence but none had symptoms of overactivity. Three patients had a weak urinary stream. Renal function was normal in 9, 4 had a glomerular filtration rate <80 ml/min/1.73 m2 , and 3 had undergone renal transplant. Erections and orgasm were experienced by the 15 patients who responded to these questions, with 4 reporting mild or medium erectile dysfunction and 1, on dialysis, reporting slow ejaculation. Post-masturbation samples of semen and urine were collected from 6 patients. One had an alkaline pH, high percentage of immotile sperm and low sperm count. Another had a high concentration of abnormal forms, and seminal fluid was present in the urine of 3 patients. Conclusions In long-term follow-up, 44% of PUV patients develop chronic renal failure or end-stage renal disease, but bladder dysfunction symptoms are infrequent. Sexual function is mostly normal. Total semen counts and motility are compatible with paternity in most patients.</description><identifier>ISSN: 1477-5131</identifier><identifier>EISSN: 1873-4898</identifier><identifier>DOI: 10.1016/j.jpurol.2011.11.006</identifier><identifier>PMID: 22154080</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adolescent ; Adult ; Bladder dysfunction ; Ejaculation - physiology ; Erectile Dysfunction - etiology ; Fertility ; Follow-Up Studies ; Humans ; Infertility, Male - etiology ; Male ; Pediatrics ; Penile Erection - physiology ; Posterior urethral valves ; Prognosis ; Retrospective Studies ; Semen analysis ; Sexual Dysfunction, Physiological - etiology ; Sexual Dysfunctions, Psychological - etiology ; Sexual function ; Surveys and Questionnaires ; Urethra - abnormalities ; Urethra - surgery ; Urethral Stricture - surgery ; Urinary Bladder - physiology ; Urinary Bladder Diseases - etiology ; Urination Disorders - etiology ; Urodynamics - physiology ; Urology ; Young Adult</subject><ispartof>Journal of pediatric urology, 2013-02, Vol.9 (1), p.38-41</ispartof><rights>Journal of Pediatric Urology Company</rights><rights>2011 Journal of Pediatric Urology Company</rights><rights>Copyright © 2011 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c417t-30d70a9144c94ad96c92c8646f6449885e353d0368c1ab7e65e7342017173b623</citedby><cites>FETCH-LOGICAL-c417t-30d70a9144c94ad96c92c8646f6449885e353d0368c1ab7e65e7342017173b623</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22154080$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>López Pereira, P</creatorcontrib><creatorcontrib>Miguel, M</creatorcontrib><creatorcontrib>Martínez Urrutia, M.J</creatorcontrib><creatorcontrib>Moreno, J.A</creatorcontrib><creatorcontrib>Marcos, M</creatorcontrib><creatorcontrib>Lobato, R</creatorcontrib><creatorcontrib>Jaureguízar, E</creatorcontrib><title>Long-term bladder function, fertility and sexual function in patients with posterior urethral valves treated in infancy</title><title>Journal of pediatric urology</title><addtitle>J Pediatr Urol</addtitle><description>Abstract Objective To address the issue of sexual function and fertility in PUV patients. Patients and methods Of 47 patients (age > 18 years) treated for PUV in infancy 28 were contactable. They were sent a standard questionnaire requesting details on voiding dysfunction symptoms, and experience of erection, orgasm and ejaculation. Results Of the 28, 16 (mean age 24 years) returned the questionnaire. Voiding frequency ranged from 3 to 10 times per day (mean = 5). Two patients had occasional mild diurnal incontinence but none had symptoms of overactivity. Three patients had a weak urinary stream. Renal function was normal in 9, 4 had a glomerular filtration rate <80 ml/min/1.73 m2 , and 3 had undergone renal transplant. Erections and orgasm were experienced by the 15 patients who responded to these questions, with 4 reporting mild or medium erectile dysfunction and 1, on dialysis, reporting slow ejaculation. Post-masturbation samples of semen and urine were collected from 6 patients. One had an alkaline pH, high percentage of immotile sperm and low sperm count. Another had a high concentration of abnormal forms, and seminal fluid was present in the urine of 3 patients. Conclusions In long-term follow-up, 44% of PUV patients develop chronic renal failure or end-stage renal disease, but bladder dysfunction symptoms are infrequent. Sexual function is mostly normal. Total semen counts and motility are compatible with paternity in most patients.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Bladder dysfunction</subject><subject>Ejaculation - physiology</subject><subject>Erectile Dysfunction - etiology</subject><subject>Fertility</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Infertility, Male - etiology</subject><subject>Male</subject><subject>Pediatrics</subject><subject>Penile Erection - physiology</subject><subject>Posterior urethral valves</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Semen analysis</subject><subject>Sexual Dysfunction, Physiological - etiology</subject><subject>Sexual Dysfunctions, Psychological - etiology</subject><subject>Sexual function</subject><subject>Surveys and Questionnaires</subject><subject>Urethra - abnormalities</subject><subject>Urethra - surgery</subject><subject>Urethral Stricture - surgery</subject><subject>Urinary Bladder - physiology</subject><subject>Urinary Bladder Diseases - etiology</subject><subject>Urination Disorders - etiology</subject><subject>Urodynamics - physiology</subject><subject>Urology</subject><subject>Young Adult</subject><issn>1477-5131</issn><issn>1873-4898</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNqFkU1v1DAQhiMEoqXwDxDykQNZ_JXYuSChqnxIK_VAe7a89oQ6eO1gO9vuv8fRlh64II00I_l935GfaZq3BG8IJv3HaTPNS4p-QzEhm1oY98-acyIFa7kc5PM6cyHajjBy1rzKecKYCUyHl80ZpaTjWOLz5n4bw8-2QNqjndfWQkLjEkxxMXxAI6TivCtHpINFGR4W7Z-ekQto1sVBKBndu3KH5phrkIsJLQnKXarig_YHyKgk0AXsanFh1MEcXzcvRu0zvHnsF83tl6uby2_t9vrr98vP29ZwIkrLsBVYD4RzM3Bth94M1Mie92PP-SBlB6xjFrNeGqJ3AvoOBOOViCCC7XrKLpr3p9w5xd8L5KL2LhvwXgeIS1YVDpUdEZJVKT9JTYo5JxjVnNxep6MiWK3I1aROyNWKXNWqyKvt3eOGZbcH-2T6y7gKPp0EUP95cJBUNpWaAesSmKJsdP_b8G-A8S44o_0vOEKe4pJCZaiIylRh9WM9-3p1QjCmkkr2B0R5qgo</recordid><startdate>20130201</startdate><enddate>20130201</enddate><creator>López Pereira, P</creator><creator>Miguel, M</creator><creator>Martínez Urrutia, M.J</creator><creator>Moreno, J.A</creator><creator>Marcos, M</creator><creator>Lobato, R</creator><creator>Jaureguízar, E</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130201</creationdate><title>Long-term bladder function, fertility and sexual function in patients with posterior urethral valves treated in infancy</title><author>López Pereira, P ; Miguel, M ; Martínez Urrutia, M.J ; Moreno, J.A ; Marcos, M ; Lobato, R ; Jaureguízar, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-30d70a9144c94ad96c92c8646f6449885e353d0368c1ab7e65e7342017173b623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Bladder dysfunction</topic><topic>Ejaculation - physiology</topic><topic>Erectile Dysfunction - etiology</topic><topic>Fertility</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Infertility, Male - etiology</topic><topic>Male</topic><topic>Pediatrics</topic><topic>Penile Erection - physiology</topic><topic>Posterior urethral valves</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Semen analysis</topic><topic>Sexual Dysfunction, Physiological - etiology</topic><topic>Sexual Dysfunctions, Psychological - etiology</topic><topic>Sexual function</topic><topic>Surveys and Questionnaires</topic><topic>Urethra - abnormalities</topic><topic>Urethra - surgery</topic><topic>Urethral Stricture - surgery</topic><topic>Urinary Bladder - physiology</topic><topic>Urinary Bladder Diseases - etiology</topic><topic>Urination Disorders - etiology</topic><topic>Urodynamics - physiology</topic><topic>Urology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>López Pereira, P</creatorcontrib><creatorcontrib>Miguel, M</creatorcontrib><creatorcontrib>Martínez Urrutia, M.J</creatorcontrib><creatorcontrib>Moreno, J.A</creatorcontrib><creatorcontrib>Marcos, M</creatorcontrib><creatorcontrib>Lobato, R</creatorcontrib><creatorcontrib>Jaureguízar, E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pediatric urology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>López Pereira, P</au><au>Miguel, M</au><au>Martínez Urrutia, M.J</au><au>Moreno, J.A</au><au>Marcos, M</au><au>Lobato, R</au><au>Jaureguízar, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term bladder function, fertility and sexual function in patients with posterior urethral valves treated in infancy</atitle><jtitle>Journal of pediatric urology</jtitle><addtitle>J Pediatr Urol</addtitle><date>2013-02-01</date><risdate>2013</risdate><volume>9</volume><issue>1</issue><spage>38</spage><epage>41</epage><pages>38-41</pages><issn>1477-5131</issn><eissn>1873-4898</eissn><abstract>Abstract Objective To address the issue of sexual function and fertility in PUV patients. Patients and methods Of 47 patients (age > 18 years) treated for PUV in infancy 28 were contactable. They were sent a standard questionnaire requesting details on voiding dysfunction symptoms, and experience of erection, orgasm and ejaculation. Results Of the 28, 16 (mean age 24 years) returned the questionnaire. Voiding frequency ranged from 3 to 10 times per day (mean = 5). Two patients had occasional mild diurnal incontinence but none had symptoms of overactivity. Three patients had a weak urinary stream. Renal function was normal in 9, 4 had a glomerular filtration rate <80 ml/min/1.73 m2 , and 3 had undergone renal transplant. Erections and orgasm were experienced by the 15 patients who responded to these questions, with 4 reporting mild or medium erectile dysfunction and 1, on dialysis, reporting slow ejaculation. Post-masturbation samples of semen and urine were collected from 6 patients. One had an alkaline pH, high percentage of immotile sperm and low sperm count. Another had a high concentration of abnormal forms, and seminal fluid was present in the urine of 3 patients. Conclusions In long-term follow-up, 44% of PUV patients develop chronic renal failure or end-stage renal disease, but bladder dysfunction symptoms are infrequent. Sexual function is mostly normal. Total semen counts and motility are compatible with paternity in most patients.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>22154080</pmid><doi>10.1016/j.jpurol.2011.11.006</doi><tpages>4</tpages></addata></record> |
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| source | ScienceDirect Journals |
| subjects | Adolescent Adult Bladder dysfunction Ejaculation - physiology Erectile Dysfunction - etiology Fertility Follow-Up Studies Humans Infertility, Male - etiology Male Pediatrics Penile Erection - physiology Posterior urethral valves Prognosis Retrospective Studies Semen analysis Sexual Dysfunction, Physiological - etiology Sexual Dysfunctions, Psychological - etiology Sexual function Surveys and Questionnaires Urethra - abnormalities Urethra - surgery Urethral Stricture - surgery Urinary Bladder - physiology Urinary Bladder Diseases - etiology Urination Disorders - etiology Urodynamics - physiology Urology Young Adult |
| title | Long-term bladder function, fertility and sexual function in patients with posterior urethral valves treated in infancy |
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