Impact of TAVI on Mitral Regurgitation: A Prospective Echocardiographic Study

• Published in: Echocardiography (Mount Kisco, N.Y.) N.Y.), 2013-03, Vol.30 (3), p.250-257
• Main Authors: Giordana, Francesca, Capriolo, Michele, Frea, Simone, Marra, Walter Grosso, Giorgi, Mauro, Bergamasco, Laura, Omedè, Pier Luigi, Sheiban, Imad, D'Amico, Maurizio, Bovolo, Virginia, Salizzoni, Stefano, La Torre, Michele, Rinaldi, Mauro, Marra, Sebastiano, Gaita, Fiorenzo, Morello, Mara
• Format: Article
• Language: English
• Subjects: Aged, 80 and over; aortic valve prosthesis; Aortic Valve Stenosis - complications; Aortic Valve Stenosis - diagnostic imaging; Aortic Valve Stenosis - surgery; echocardiography; Echocardiography - methods; Female; Heart Valve Prosthesis Implantation; Humans; Male; mitral regurgitation; Mitral Valve Insufficiency - complications; Mitral Valve Insufficiency - diagnostic imaging; Mitral Valve Insufficiency - surgery; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome
• ISSN: 0742-2822; 1540-8175
• DOI: 10.1111/echo.12050

Objective: This study aims to assess changes in mitral regurgitation (MR) severity after transcatheter aortic valve implantation (TAVI). Background: Existing data on MR after TAVI are contradictory. Methods: Thirty‐five patients with MR graded ≥ 2+ were followed after undergoing TAVI with either the Edwards Sapien or CoreValve device. Echocardiography was performed the week before and 3 months after the procedure. MR was graded on a scale of 0 to 4+, classified as organic or functional, and the effective regurgitant orifice area (EROA) and MR index were calculated. Results: At baseline, MR was graded 4+ in 4 (11.4%) patients, 3+  in 10 (28.6%), and 2+ in 21 (60%). At follow‐up, MR was graded at 3+ in 4 (11.4%) patients, 2+ in 8 (22.9%), and 1+ in 19 (54.3%); 4 (11.4%) exhibited no MR. EROA (24.4 ± 11.5 mm2 pre‐TAVI vs. 11.2 ± 10.3 mm2 post‐TAVI, P