Relation of B-Type Natriuretic Peptide Level in Heart Failure to Sudden Cardiac Death in Patients With and Without QT Interval Prolongation

Increased levels of B-type natriuretic peptide (BNP) are associated with prolongation of the action potential in ventricular myocardium. We investigated the relation of a BNP increase, QT interval, and sudden cardiac death (SCD) in the presence of heart failure (HF). We enrolled 398 patients with HF...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of cardiology 2013-03, Vol.111 (6), p.886-890
Main Authors: Vrtovec, Bojan, MD, PhD, Knezevic, Ivan, MD, Poglajen, Gregor, MD, PhD, Sebestjen, Miran, MD, PhD, Okrajsek, Renata, MD, PhD, Haddad, François, MD
Format: Article
Language:English
Subjects:
Aged
Biomarkers - blood
Cardiac arrhythmia
Cardiovascular
Chi-Square Distribution
Death, Sudden, Cardiac - epidemiology
Death, Sudden, Cardiac - etiology
Drug therapy
Echocardiography
Electrocardiography
Female
Heart attacks
Heart failure
Heart Failure - blood
Heart Failure - complications
Heart Failure - epidemiology
Humans
Long QT Syndrome - blood
Long QT Syndrome - complications
Long QT Syndrome - epidemiology
Male
Middle Aged
Mortality
Natriuretic Peptide, Brain - blood
Proportional Hazards Models
Prospective Studies
Risk Factors
Survival Rate
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Increased levels of B-type natriuretic peptide (BNP) are associated with prolongation of the action potential in ventricular myocardium. We investigated the relation of a BNP increase, QT interval, and sudden cardiac death (SCD) in the presence of heart failure (HF). We enrolled 398 patients with HF, New York Heart Association class III or IV, and left ventricular ejection fraction
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2012.11.041