Extracellular matrix scaffolds for cartilage and bone regeneration

Highlights ► Extracellular matrix scaffolds provide a bioactive platform for tissue regeneration. ► Osteochondral defect repair remains a great orthopedic and socioeconomic burden. ► We describe cartilage and bone decellularization and possible future directions. ► Extracellular matrix scaffolds hol...

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Bibliographic Details
Published in:Trends in biotechnology (Regular ed.) 2013-03, Vol.31 (3), p.169-176
Main Authors: Benders, Kim E.M, Weeren, P. René van, Badylak, Stephen F, Saris, Daniël B.F, Dhert, Wouter J.A, Malda, Jos
Format: Article
Language:English
Subjects:
Biomechanics
Biomedical materials
Bone Regeneration
Cartilage - growth & development
Defects
Extracellular matrix
Extracellular Matrix - metabolism
Guided Tissue Regeneration - methods
Internal Medicine
Regenerative Medicine - methods
Tissue engineering
Tissue Scaffolds
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Summary:Highlights ► Extracellular matrix scaffolds provide a bioactive platform for tissue regeneration. ► Osteochondral defect repair remains a great orthopedic and socioeconomic burden. ► We describe cartilage and bone decellularization and possible future directions. ► Extracellular matrix scaffolds hold great promise for osteochondral defect repair.
ISSN:0167-7799
1879-3096
DOI:10.1016/j.tibtech.2012.12.004