Risk Score for the Prediction of Contrast-Induced Nephropathy in Elderly Patients Undergoing Percutaneous Coronary Intervention

We developed a risk score for contrast-induced nephropathy (CIN) in elderly patients (n = 668) before percutaneous coronary intervention (PCI). Another 277 elderly patients were studied for validation. Based on the odds ratio, risk factors were assigned a weighted integer; the sum of the integers wa...

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Bibliographic Details
Published in:Angiology 2013-04, Vol.64 (3), p.188-194
Main Authors: Fu, Naikuan, Li, Ximing, Yang, Shicheng, Chen, Yongli, Li, Qiong, Jin, Dongxia, Cong, Hongliang
Format: Article
Language:English
Subjects:
Aged
Angioplasty, Balloon, Coronary
Contrast Media - adverse effects
Female
Glomerular Filtration Rate
Humans
Kidney Diseases - chemically induced
Kidney Diseases - epidemiology
Male
Myocardial Infarction - epidemiology
Retrospective Studies
Risk Assessment
Risk Factors
Stroke Volume
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Summary:We developed a risk score for contrast-induced nephropathy (CIN) in elderly patients (n = 668) before percutaneous coronary intervention (PCI). Another 277 elderly patients were studied for validation. Based on the odds ratio, risk factors were assigned a weighted integer; the sum of the integers was the risk score. Among the 668 elderly patients, 105 (15.7%) experienced CIN. There were 9 risk factors for CIN (with weighted integer): estimated glomerular filtration rate (eGFR) 200 mL (2). The incidence of CIN was 3.4%, 11.9%, 36.9%, and 69.8% in the low-risk (≤4), moderate risk (5-8), high-risk (9-12), and very-high-risk groups (≥13). The model demonstrated good discriminative power in the validation population (c statistic = 0.79). This score can be used to plan preventative measures.
ISSN:0003-3197
1940-1574
DOI:10.1177/0003319712467224