Stimuli-responsive polymers: Biomedical applications and challenges for clinical translation

Over the past 25years many interesting biomedical uses have been proposed for stimuli-responsive polymers, including uses in diagnostics, drug delivery, tissue engineering (regenerative medicine), and cell culture. This article briefly overviews the field of stimuli-responsive polymers and describes...

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Bibliographic Details
Published in:Advanced drug delivery reviews 2013-01, Vol.65 (1), p.10-16
Main Author: Hoffman, Allan S.
Format: Article
Language:English
Subjects:
Biocompatible Materials - administration & dosage
Biocompatible Materials - chemistry
Biomedical applications and challenges for clinical translation
Biomedical Research - methods
Drug Delivery Systems - methods
Polymers - administration & dosage
Polymers - chemistry
Stimuli-responsive polymers
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Summary:Over the past 25years many interesting biomedical uses have been proposed for stimuli-responsive polymers, including uses in diagnostics, drug delivery, tissue engineering (regenerative medicine), and cell culture. This article briefly overviews the field of stimuli-responsive polymers and describes some of the most successful biomedical applications to date of such “smart” polymers. Other interesting potential applications are also discussed. The major barriers to future clinical translation of smart polymers are also critically discussed. [Display omitted]
ISSN:0169-409X
1872-8294
DOI:10.1016/j.addr.2012.11.004