Sensing Capability of Molecularly Imprinted Self-Assembled Monolayer Using Terphenylpropanethiol

A molecularly imprinted self-assembled monolayer (SAM) was fabricated on a gold plate by forming a monolayer with both thiol compound and the template molecule, and removing the template molecules by solvent extraction. 1-Dodecanethiol (DDT), 1-hexadecanethiol (HDT), [1,1′:4′,1′′-terphenyl]-4-thiol...

Full description

Saved in:
Bibliographic Details
Published in:Particulate science and technology 2012-11, Vol.30 (6), p.543-552
Main Authors: Shin, Min Jae, Yang, Minhee, Shin, Jae Sup
Format: Article
Language:English
Subjects:
Chemical compounds
Cholesterol
DDT
Detection
Electrodes
Gold
imprinting
Molecules
Monolayers
self-assembled monolayer
Self-assembled monolayers
sensor
Solvents
terphenylthiol
Thiols
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A molecularly imprinted self-assembled monolayer (SAM) was fabricated on a gold plate by forming a monolayer with both thiol compound and the template molecule, and removing the template molecules by solvent extraction. 1-Dodecanethiol (DDT), 1-hexadecanethiol (HDT), [1,1′:4′,1′′-terphenyl]-4-thiol (TPT), and [1,1′:4′,1′′-terphenyl]-4-propanethiol (TPPT) were used as the thiol compounds. Cholesterol was used as the template molecule, and cholesterol, cholic acid, and deoxycholic acid were used as the substrate molecules. Cyclic voltammograms were obtained using these imprinted gold plates as a working electrode, with Ag/AgCl reference electrode and Pt counter-electrode. Potassium ferricyanide was used as a background material for oxidation and reduction. These imprinted monolayers were capable of discriminating cholesterol that had been imprinted. The order of sensing capability of the thiol compounds was TPPT > HDT > TPT > DDT.
ISSN:0272-6351
1548-0046
DOI:10.1080/02726351.2011.613895