Serum Vitamin D Increases with Weight Loss in Obese Subjects 6 Months After Roux-en-Y Gastric Bypass

• Published in: Obesity surgery 2013-04, Vol.23 (4), p.486-493
• Main Authors: Coupaye, Muriel, Breuil, Marie Christine, Rivière, Pauline, Castel, Benjamin, Bogard, Catherine, Dupré, Thierry, Msika, Simon, Ledoux, Séverine
• Format: Article
• Language: English
• Subjects: Adult; Body Mass Index; Calcium - blood; Calcium - metabolism; Calcium - urine; Clinical Research; Cohort Studies; Dietary Supplements; Female; Gastric Bypass - adverse effects; Humans; Malabsorption Syndromes - diet therapy; Malabsorption Syndromes - etiology; Malabsorption Syndromes - metabolism; Malabsorption Syndromes - surgery; Malabsorption Syndromes - urine; Male; Medicine; Medicine & Public Health; Obesity, Morbid - blood; Obesity, Morbid - diet therapy; Obesity, Morbid - metabolism; Obesity, Morbid - surgery; Parathyroid Hormone - blood; Prospective Studies; Surgery; Time Factors; Vitamin D - administration & dosage; Vitamin D - blood; Vitamin D - metabolism; Vitamin D - urine; Weight Loss
• ISSN: 0960-8923; 1708-0428
• DOI: 10.1007/s11695-012-0813-y

Background Malabsorptive surgical procedures lead to deficiencies in fat-soluble vitamins. However, results concerning serum vitamin D (25OHD) after gastric bypass (GBP) are controversial. The aim of the study was to assess the influence of GBP on 25OHD and calcium metabolism. Methods Parameters of calcium metabolism were evaluated in 202 obese subjects before and 6 months after GBP. Thirty of them were matched for age, gender, weight, skin color, and season with 30 subjects who underwent sleeve gastrectomy (SG). A multivitamin preparation that provides 200 to 500 IU vitamin D3 per day was systematically prescribed after surgery. Results In the 202 patients after GBP, serum 25OHD significantly increased from 13.4 ± 9.1 to 22.8 ± 11.3 ng/ml ( p