Genomic Sequencing Reveals Mutations Potentially Related to the Overattenuation of a Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus

• Published in: Clinical and Vaccine Immunology 2013-04, Vol.20 (4), p.613-619
• Main Authors: Yu, Xiuling, Chen, Nanhua, Deng, Xiaoyu, Cao, Zhen, Han, Wei, Hu, Dongmei, Wu, Jiajun, Zhang, Shuo, Wang, Baoyue, Gu, Xiaoxue, Tian, Kegong
• Format: Article
• Language: English
• Subjects: 3' Untranslated Regions; 5' Untranslated Regions; Amino acid substitution; Animals; Cell Line; Clinical Immunology; Disease Models, Animal; Genome, Viral; Mutation; Point Mutation; Porcine Reproductive and Respiratory Syndrome - immunology; Porcine Reproductive and Respiratory Syndrome - prevention & control; Porcine Reproductive and Respiratory Syndrome - virology; Porcine respiratory and reproductive syndrome virus; Porcine respiratory and reproductive syndrome virus - genetics; Porcine respiratory and reproductive syndrome virus - growth & development; Porcine respiratory and reproductive syndrome virus - immunology; Porcine respiratory and reproductive syndrome virus - pathogenicity; RNA, Viral - genetics; Sequence Analysis, DNA; Serial Passage; Survival Analysis; Swine; Viral Nonstructural Proteins - genetics; Viral Vaccines - administration & dosage; Viral Vaccines - genetics; Viral Vaccines - immunology; Virulence
• ISSN: 1556-6811; 1556-679X; 1556-679X
• DOI: 10.1128/CVI.00672-12

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