Patent foramen ovale and migraine: What is the relationship between the two?

Abstract There is conflicting evidence on the causal relationship of patent foramen ovale (PFO) in migraine. This review will examine the pathophysiological relevance of PFO in migraine, the epidemiological evidence of PFO causing migraine, and the existing evidence on the effectiveness of closure o...

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Bibliographic Details
Published in:Journal of cardiology 2013-04, Vol.61 (4), p.256-259
Main Authors: Sathasivam, Sivarani, MBBS, Sathasivam, Sivakumar, MB BCh, MRCP UK, LLM, PhD
Format: Article
Language:English
Subjects:
Cardiovascular
Clinical Trials as Topic
Congenital
Foramen Ovale, Patent - complications
Foramen Ovale, Patent - physiopathology
Foramen Ovale, Patent - surgery
Heart defects
Humans
Migraine
Migraine Disorders - etiology
Migraine Disorders - therapy
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Summary:Abstract There is conflicting evidence on the causal relationship of patent foramen ovale (PFO) in migraine. This review will examine the pathophysiological relevance of PFO in migraine, the epidemiological evidence of PFO causing migraine, and the existing evidence on the effectiveness of closure of PFO on the symptomatology of migraine. From the current available evidence, the role of PFO in migraine is debatable, and interventions such as closure of PFO cannot yet be considered routine treatment of migraine.
ISSN:0914-5087
1876-4738
DOI:10.1016/j.jjcc.2012.12.005