The relation between mean platelet volume and coronary collateral vessels in patients with acute coronary syndromes

Abstract Objective Elevated mean platelet volume (MPV) has been proposed as a risk factor for coronary artery disease (CAD) and is associated with poor clinical outcome in acute coronary syndrome (ACS). We aimed to evaluate the association of MPV with presence of coronary collateral vessel (CCV) in...

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Bibliographic Details
Published in:Journal of cardiology 2013-04, Vol.61 (4), p.295-298
Main Authors: Duran, Mustafa, MD, Gunebakmaz, Ozgur, MD, Uysal, Onur Kadir, MD, Ocak, Ayse, MD, Yilmaz, Yucel, MD, Arinc, Huseyin, MD, Eryol, Namik K., MD, Ergin, Ali, MD, Kaya, Mehmet Gungor, MD
Format: Article
Language:English
Subjects:
Acute coronary syndrome
Acute Coronary Syndrome - etiology
Acute Coronary Syndrome - physiopathology
Aged
Blood Platelets - pathology
Blood Volume
Cardiovascular
Collateral Circulation - physiology
Coronary Circulation - physiology
Coronary collateral vessel
Coronary Vessels - physiopathology
Female
Humans
Male
Mean platelet volume
Middle Aged
Prognosis
Prospective Studies
Risk Factors
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Summary:Abstract Objective Elevated mean platelet volume (MPV) has been proposed as a risk factor for coronary artery disease (CAD) and is associated with poor clinical outcome in acute coronary syndrome (ACS). We aimed to evaluate the association of MPV with presence of coronary collateral vessel (CCV) in patients with ACS. Methods A total of 417 patients with ACS were included in the study. All patients underwent coronary angiography on the first day after admission and patients with a greater than or equal to 80% obstruction in at least one epicardial coronary artery were included in the study. The CCVs are graded according to the Rentrop scoring system and a Rentrop grade 0 was accepted as no CCV development (Group 1), Rentrop Grade 1–2–3 were accepted as presence of CCV development (Group 2). Results The median of MPV was 9.1 ± 1.4 fl. Mean age was 60 ± 12 year. Group 1 consisted of 233 (55.9%) patients and Group 2 consisted of 184 (44.1%) patients. Presence of CCV was significantly associated with high levels of MPV ( p = 0.005). Presence of CCV was also associated with presence of diabetes and systolic blood pressure. Conclusion High MPV on admission was associated with presence of CCV in patients with ACS.
ISSN:0914-5087
1876-4738
DOI:10.1016/j.jjcc.2012.12.011