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Nutritional status of geriatric outpatients with systolic heart failure and its prognostic value regarding death or hospitalization, biomarkers and quality of life

INTRODUCTION: The prevalence of malnutrition in ambulatory patients with heart failure is difficult to determine, depending on the timing and methodology. OBJECTIVE: To determine the nutritional status of outpatients with systolic heart failure with the Mini Nutritional Assessment (MNA) full and sho...

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Published in:The Journal of nutrition, health & aging health & aging, 2013-04, Vol.17 (4), p.300-304
Main Authors: Sargento, Luis, Satendra, M, Almeida, I, Sousa, C, Gomes, S, Salazar, F, Lousada, N, Palma dos Reis, R
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container_title The Journal of nutrition, health & aging
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creator Sargento, Luis
Satendra, M
Almeida, I
Sousa, C
Gomes, S
Salazar, F
Lousada, N
Palma dos Reis, R
description INTRODUCTION: The prevalence of malnutrition in ambulatory patients with heart failure is difficult to determine, depending on the timing and methodology. OBJECTIVE: To determine the nutritional status of outpatients with systolic heart failure with the Mini Nutritional Assessment (MNA) full and short-form versions, and evaluate its relationship with the short-term prognosis, biomarkers and quality of life. METHODS: Fifty consecutive (70% male), geriatric (74.3+ 6.2years old) stable outpatient with heart failure (NYHA class II 68%, III 32%) and left ventricular ejection fraction of 26.7 +11.5% were included and followed during 12 months. At a routine visit to the heart failure clinic, the MNA, the Minnesota Living with Heart Failure questionnaire (MLHFQ) were applied. According to the MNA screening score the nutritional status was classified using the MNA full (MNA-F) and the short-form (MNA-F) versions of the questionnaire. The recorded events were death and hospitalization. Statistics: The-survival and hospitalizations curves were evaluated with the Log-Rank test and Cox Regression analysis. The association between parameters was analyzed with the Pearson and Spearmann correlation coefficient. RESULTS: (1) The mortality and hospitalization rates were 12% and 42%, respectively. (2) With the MNA-SF 7.6% of the patients had malnutrition and 20% were at risk of malnutrition. There was a good agreement (90%) between the MNA-SF and the MNA-F classifications. (3) There was a significant relationship between the MNA screening score and the MLHFQ (rs= −0.592 p
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OBJECTIVE: To determine the nutritional status of outpatients with systolic heart failure with the Mini Nutritional Assessment (MNA) full and short-form versions, and evaluate its relationship with the short-term prognosis, biomarkers and quality of life. METHODS: Fifty consecutive (70% male), geriatric (74.3+ 6.2years old) stable outpatient with heart failure (NYHA class II 68%, III 32%) and left ventricular ejection fraction of 26.7 +11.5% were included and followed during 12 months. At a routine visit to the heart failure clinic, the MNA, the Minnesota Living with Heart Failure questionnaire (MLHFQ) were applied. According to the MNA screening score the nutritional status was classified using the MNA full (MNA-F) and the short-form (MNA-F) versions of the questionnaire. The recorded events were death and hospitalization. Statistics: The-survival and hospitalizations curves were evaluated with the Log-Rank test and Cox Regression analysis. The association between parameters was analyzed with the Pearson and Spearmann correlation coefficient. RESULTS: (1) The mortality and hospitalization rates were 12% and 42%, respectively. (2) With the MNA-SF 7.6% of the patients had malnutrition and 20% were at risk of malnutrition. There was a good agreement (90%) between the MNA-SF and the MNA-F classifications. (3) There was a significant relationship between the MNA screening score and the MLHFQ (rs= −0.592 p&lt;0.00l), Nt-ProBNP (rs= −0.49 p&lt;0.001) and total plasma protein (r= 0.672 p=0.006); (3) The-MNA-SF nutritional classification was associated with the 12 months survival (Log-Rank p=0.044) and hospitalization (Log-Rank p=0.005) curves. (4) Those patients with malnutrition by the MNA-SF were at greater risk of death (HR= 8.0 p=0.059) and hospitalization (HR 8.1 p=0.008). CONCLUSION: The MNA is useful for the evaluation of the nutritional status of elderly outpatients with systolic heart failure. It is a good predictor of the short-term outcome and is also associated with the quality of life and Nt-ProBNP.</description><identifier>ISSN: 1279-7707</identifier><identifier>EISSN: 1760-4788</identifier><identifier>DOI: 10.1007/s12603-013-0030-y</identifier><identifier>PMID: 23538649</identifier><language>eng</language><publisher>Paris: Springer-Verlag</publisher><subject>Aged ; Aged, 80 and over ; Aging ; biomarkers ; Biomarkers - blood ; blood proteins ; correlation ; death ; elderly ; Female ; Geriatric Assessment - methods ; Geriatrics ; Geriatrics/Gerontology ; heart failure ; Heart Failure, Systolic - complications ; Heart Failure, Systolic - physiopathology ; Hospitalization ; Humans ; Male ; malnutrition ; Malnutrition - complications ; Malnutrition - diagnosis ; Malnutrition - epidemiology ; Medicine ; Medicine &amp; Public Health ; mortality ; Natriuretic Peptide, Brain - blood ; Neurosciences ; Nutrition ; Nutrition Assessment ; Nutritional Status ; Outpatients ; patients ; Peptide Fragments - blood ; Prevalence ; Primary Care Medicine ; Prognosis ; Proportional Hazards Models ; Quality of Life ; Quality of Life Research ; questionnaires ; regression analysis ; risk ; screening ; Surveys and Questionnaires</subject><ispartof>The Journal of nutrition, health &amp; aging, 2013-04, Vol.17 (4), p.300-304</ispartof><rights>Serdi and Springer-Verlag France 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c411t-ddb99ad01e273457a7ff4c5d7fbd4a36c925217c21531f7c785908083273cd923</citedby><cites>FETCH-LOGICAL-c411t-ddb99ad01e273457a7ff4c5d7fbd4a36c925217c21531f7c785908083273cd923</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23538649$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sargento, Luis</creatorcontrib><creatorcontrib>Satendra, M</creatorcontrib><creatorcontrib>Almeida, I</creatorcontrib><creatorcontrib>Sousa, C</creatorcontrib><creatorcontrib>Gomes, S</creatorcontrib><creatorcontrib>Salazar, F</creatorcontrib><creatorcontrib>Lousada, N</creatorcontrib><creatorcontrib>Palma dos Reis, R</creatorcontrib><title>Nutritional status of geriatric outpatients with systolic heart failure and its prognostic value regarding death or hospitalization, biomarkers and quality of life</title><title>The Journal of nutrition, health &amp; aging</title><addtitle>J Nutr Health Aging</addtitle><addtitle>J Nutr Health Aging</addtitle><description>INTRODUCTION: The prevalence of malnutrition in ambulatory patients with heart failure is difficult to determine, depending on the timing and methodology. OBJECTIVE: To determine the nutritional status of outpatients with systolic heart failure with the Mini Nutritional Assessment (MNA) full and short-form versions, and evaluate its relationship with the short-term prognosis, biomarkers and quality of life. METHODS: Fifty consecutive (70% male), geriatric (74.3+ 6.2years old) stable outpatient with heart failure (NYHA class II 68%, III 32%) and left ventricular ejection fraction of 26.7 +11.5% were included and followed during 12 months. At a routine visit to the heart failure clinic, the MNA, the Minnesota Living with Heart Failure questionnaire (MLHFQ) were applied. According to the MNA screening score the nutritional status was classified using the MNA full (MNA-F) and the short-form (MNA-F) versions of the questionnaire. The recorded events were death and hospitalization. Statistics: The-survival and hospitalizations curves were evaluated with the Log-Rank test and Cox Regression analysis. The association between parameters was analyzed with the Pearson and Spearmann correlation coefficient. RESULTS: (1) The mortality and hospitalization rates were 12% and 42%, respectively. (2) With the MNA-SF 7.6% of the patients had malnutrition and 20% were at risk of malnutrition. There was a good agreement (90%) between the MNA-SF and the MNA-F classifications. (3) There was a significant relationship between the MNA screening score and the MLHFQ (rs= −0.592 p&lt;0.00l), Nt-ProBNP (rs= −0.49 p&lt;0.001) and total plasma protein (r= 0.672 p=0.006); (3) The-MNA-SF nutritional classification was associated with the 12 months survival (Log-Rank p=0.044) and hospitalization (Log-Rank p=0.005) curves. (4) Those patients with malnutrition by the MNA-SF were at greater risk of death (HR= 8.0 p=0.059) and hospitalization (HR 8.1 p=0.008). CONCLUSION: The MNA is useful for the evaluation of the nutritional status of elderly outpatients with systolic heart failure. 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Satendra, M ; Almeida, I ; Sousa, C ; Gomes, S ; Salazar, F ; Lousada, N ; Palma dos Reis, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-ddb99ad01e273457a7ff4c5d7fbd4a36c925217c21531f7c785908083273cd923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aging</topic><topic>biomarkers</topic><topic>Biomarkers - blood</topic><topic>blood proteins</topic><topic>correlation</topic><topic>death</topic><topic>elderly</topic><topic>Female</topic><topic>Geriatric Assessment - methods</topic><topic>Geriatrics</topic><topic>Geriatrics/Gerontology</topic><topic>heart failure</topic><topic>Heart Failure, Systolic - complications</topic><topic>Heart Failure, Systolic - physiopathology</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Male</topic><topic>malnutrition</topic><topic>Malnutrition - complications</topic><topic>Malnutrition - diagnosis</topic><topic>Malnutrition - epidemiology</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>mortality</topic><topic>Natriuretic Peptide, Brain - blood</topic><topic>Neurosciences</topic><topic>Nutrition</topic><topic>Nutrition Assessment</topic><topic>Nutritional Status</topic><topic>Outpatients</topic><topic>patients</topic><topic>Peptide Fragments - blood</topic><topic>Prevalence</topic><topic>Primary Care Medicine</topic><topic>Prognosis</topic><topic>Proportional Hazards Models</topic><topic>Quality of Life</topic><topic>Quality of Life Research</topic><topic>questionnaires</topic><topic>regression analysis</topic><topic>risk</topic><topic>screening</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sargento, Luis</creatorcontrib><creatorcontrib>Satendra, M</creatorcontrib><creatorcontrib>Almeida, I</creatorcontrib><creatorcontrib>Sousa, C</creatorcontrib><creatorcontrib>Gomes, S</creatorcontrib><creatorcontrib>Salazar, F</creatorcontrib><creatorcontrib>Lousada, N</creatorcontrib><creatorcontrib>Palma dos Reis, R</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of nutrition, health &amp; aging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sargento, Luis</au><au>Satendra, M</au><au>Almeida, I</au><au>Sousa, C</au><au>Gomes, S</au><au>Salazar, F</au><au>Lousada, N</au><au>Palma dos Reis, R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nutritional status of geriatric outpatients with systolic heart failure and its prognostic value regarding death or hospitalization, biomarkers and quality of life</atitle><jtitle>The Journal of nutrition, health &amp; aging</jtitle><stitle>J Nutr Health Aging</stitle><addtitle>J Nutr Health Aging</addtitle><date>2013-04-01</date><risdate>2013</risdate><volume>17</volume><issue>4</issue><spage>300</spage><epage>304</epage><pages>300-304</pages><issn>1279-7707</issn><eissn>1760-4788</eissn><abstract>INTRODUCTION: The prevalence of malnutrition in ambulatory patients with heart failure is difficult to determine, depending on the timing and methodology. OBJECTIVE: To determine the nutritional status of outpatients with systolic heart failure with the Mini Nutritional Assessment (MNA) full and short-form versions, and evaluate its relationship with the short-term prognosis, biomarkers and quality of life. METHODS: Fifty consecutive (70% male), geriatric (74.3+ 6.2years old) stable outpatient with heart failure (NYHA class II 68%, III 32%) and left ventricular ejection fraction of 26.7 +11.5% were included and followed during 12 months. At a routine visit to the heart failure clinic, the MNA, the Minnesota Living with Heart Failure questionnaire (MLHFQ) were applied. According to the MNA screening score the nutritional status was classified using the MNA full (MNA-F) and the short-form (MNA-F) versions of the questionnaire. The recorded events were death and hospitalization. Statistics: The-survival and hospitalizations curves were evaluated with the Log-Rank test and Cox Regression analysis. The association between parameters was analyzed with the Pearson and Spearmann correlation coefficient. RESULTS: (1) The mortality and hospitalization rates were 12% and 42%, respectively. (2) With the MNA-SF 7.6% of the patients had malnutrition and 20% were at risk of malnutrition. There was a good agreement (90%) between the MNA-SF and the MNA-F classifications. (3) There was a significant relationship between the MNA screening score and the MLHFQ (rs= −0.592 p&lt;0.00l), Nt-ProBNP (rs= −0.49 p&lt;0.001) and total plasma protein (r= 0.672 p=0.006); (3) The-MNA-SF nutritional classification was associated with the 12 months survival (Log-Rank p=0.044) and hospitalization (Log-Rank p=0.005) curves. (4) Those patients with malnutrition by the MNA-SF were at greater risk of death (HR= 8.0 p=0.059) and hospitalization (HR 8.1 p=0.008). CONCLUSION: The MNA is useful for the evaluation of the nutritional status of elderly outpatients with systolic heart failure. It is a good predictor of the short-term outcome and is also associated with the quality of life and Nt-ProBNP.</abstract><cop>Paris</cop><pub>Springer-Verlag</pub><pmid>23538649</pmid><doi>10.1007/s12603-013-0030-y</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
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ispartof The Journal of nutrition, health & aging, 2013-04, Vol.17 (4), p.300-304
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1760-4788
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source Springer Nature
subjects Aged
Aged, 80 and over
Aging
biomarkers
Biomarkers - blood
blood proteins
correlation
death
elderly
Female
Geriatric Assessment - methods
Geriatrics
Geriatrics/Gerontology
heart failure
Heart Failure, Systolic - complications
Heart Failure, Systolic - physiopathology
Hospitalization
Humans
Male
malnutrition
Malnutrition - complications
Malnutrition - diagnosis
Malnutrition - epidemiology
Medicine
Medicine & Public Health
mortality
Natriuretic Peptide, Brain - blood
Neurosciences
Nutrition
Nutrition Assessment
Nutritional Status
Outpatients
patients
Peptide Fragments - blood
Prevalence
Primary Care Medicine
Prognosis
Proportional Hazards Models
Quality of Life
Quality of Life Research
questionnaires
regression analysis
risk
screening
Surveys and Questionnaires
title Nutritional status of geriatric outpatients with systolic heart failure and its prognostic value regarding death or hospitalization, biomarkers and quality of life
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