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Bidirectional Myoblast-Pericyte Plasticity

Microvascular pericytes are able to generate multiple mesenchymal cell types, including skeletal muscle myoblasts. Cappellari et al. (2013) report in this issue of Developmental Cell that myoblasts can return the favor by generating pericytes via the action of Dll4 Notch ligand and PDGF-BB.

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Bibliographic Details
Published in:Developmental cell 2013-03, Vol.24 (6), p.563-564
Main Author: Stallcup, William B.
Format: Article
Language:English
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Summary:Microvascular pericytes are able to generate multiple mesenchymal cell types, including skeletal muscle myoblasts. Cappellari et al. (2013) report in this issue of Developmental Cell that myoblasts can return the favor by generating pericytes via the action of Dll4 Notch ligand and PDGF-BB.
ISSN:1534-5807
1878-1551
DOI:10.1016/j.devcel.2013.02.018