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Applicability of sheep and pig models for cancellous bone in human vertebral bodies
The mineral content of cancellous bone from sheep and pig vertebral bodies was determined by ashing at 800 °C. The results were compared with published results for human vertebral cancellous bone. The results for sheep (0.37 ± 0.06 g cm−3, mean ± standard deviation) were not significantly different...
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Published in: | Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine Journal of engineering in medicine, 2012-01, Vol.226 (1), p.76-78 |
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description | The mineral content of cancellous bone from sheep and pig vertebral bodies was determined by ashing at 800 °C. The results were compared with published results for human vertebral cancellous bone. The results for sheep (0.37 ± 0.06 g cm−3, mean ± standard deviation) were not significantly different (p = 0.127) to those from pigs (0.33 ± 0.03 g cm−3). The results from both species were significantly higher (p |
doi_str_mv | 10.1177/0954411911426807 |
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The results were compared with published results for human vertebral cancellous bone. The results for sheep (0.37 ± 0.06 g cm−3, mean ± standard deviation) were not significantly different (p = 0.127) to those from pigs (0.33 ± 0.03 g cm−3). The results from both species were significantly higher (p < 0.001) than those from human bones (0.15 ± 0.02 g cm−3). This means that cancellous bone from sheep and pig vertebral bodies is not a good model for corresponding human bone. However, sheep and pig bone are useful, for example, for providing stringent tests of cutting instruments to be used in human spinal surgery.</description><identifier>ISSN: 0954-4119</identifier><identifier>EISSN: 2041-3033</identifier><identifier>DOI: 10.1177/0954411911426807</identifier><identifier>PMID: 22888588</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Animals ; Back surgery ; Bone Density - physiology ; Bone marrow ; Comparative analysis ; Hogs ; Human subjects ; Humans ; Sheep ; Sheep - physiology ; Species Specificity ; Spine - physiology ; Swine - physiology</subject><ispartof>Proceedings of the Institution of Mechanical Engineers. 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Part H, Journal of engineering in medicine</title><addtitle>Proc Inst Mech Eng H</addtitle><description>The mineral content of cancellous bone from sheep and pig vertebral bodies was determined by ashing at 800 °C. The results were compared with published results for human vertebral cancellous bone. The results for sheep (0.37 ± 0.06 g cm−3, mean ± standard deviation) were not significantly different (p = 0.127) to those from pigs (0.33 ± 0.03 g cm−3). The results from both species were significantly higher (p < 0.001) than those from human bones (0.15 ± 0.02 g cm−3). This means that cancellous bone from sheep and pig vertebral bodies is not a good model for corresponding human bone. However, sheep and pig bone are useful, for example, for providing stringent tests of cutting instruments to be used in human spinal surgery.</description><subject>Animals</subject><subject>Back surgery</subject><subject>Bone Density - physiology</subject><subject>Bone marrow</subject><subject>Comparative analysis</subject><subject>Hogs</subject><subject>Human subjects</subject><subject>Humans</subject><subject>Sheep</subject><subject>Sheep - physiology</subject><subject>Species Specificity</subject><subject>Spine - physiology</subject><subject>Swine - physiology</subject><issn>0954-4119</issn><issn>2041-3033</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqFkctLAzEQxoMotlbvniR48rKa52ZzLMUXFDyo5yWbzLZb9mXSFfrfm9KqUBAvGZL5zTeT-RC6pOSWUqXuiJZCUKopFSzNiDpCY0YETTjh_BiNt-lkmx-hsxBWhBBKSXqKRoxlWSazbIxep31fV9YUVV2tN7grcVgC9Ni0DvfVAjedgzrgsvPYmtZCXXdDwEXXAq5avBwa0-JP8GsovKnju6sgnKOT0tQBLvZxgt4f7t9mT8n85fF5Np0nlmu1TqQtpNNcWi2JlYyUjshMG2ZKbo2iqVDagQZhKBeWlZli8WbTElSaUqccn6CbnW7vu48BwjpvqrAd0bQQp8wpZ5wxzZj4H40LkzwVUkX0-gBddYNv40dyTVMWoXhMENlB1ncheCjz3leN8ZuolG-tyQ-tiSVXe92haMD9FHx7EYFkBwSzgN-mfwp-AX1ClGI</recordid><startdate>201201</startdate><enddate>201201</enddate><creator>Jabbary Aslani, Farnaz</creator><creator>Hukins, David WL</creator><creator>Shepherd, Duncan ET</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope><scope>7QP</scope></search><sort><creationdate>201201</creationdate><title>Applicability of sheep and pig models for cancellous bone in human vertebral bodies</title><author>Jabbary Aslani, Farnaz ; Hukins, David WL ; Shepherd, Duncan ET</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c397t-5cb5d935c950c520fd0589a2af3ca716479de9e4a134c2f872e9ec6fe7661d7d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Animals</topic><topic>Back surgery</topic><topic>Bone Density - physiology</topic><topic>Bone marrow</topic><topic>Comparative analysis</topic><topic>Hogs</topic><topic>Human subjects</topic><topic>Humans</topic><topic>Sheep</topic><topic>Sheep - physiology</topic><topic>Species Specificity</topic><topic>Spine - physiology</topic><topic>Swine - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jabbary Aslani, Farnaz</creatorcontrib><creatorcontrib>Hukins, David WL</creatorcontrib><creatorcontrib>Shepherd, Duncan ET</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Calcium & Calcified Tissue Abstracts</collection><jtitle>Proceedings of the Institution of Mechanical Engineers. 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subjects | Animals Back surgery Bone Density - physiology Bone marrow Comparative analysis Hogs Human subjects Humans Sheep Sheep - physiology Species Specificity Spine - physiology Swine - physiology |
title | Applicability of sheep and pig models for cancellous bone in human vertebral bodies |
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