Life-event specificity: bipolar disorder compared with unipolar depression

Little is known about the impact of different types of stressful events (for example divorce v. bereavement) on unipolar depression compared with bipolar disorder. Inconsistencies exist concerning the association between independent events (beyond an individual's control, such as bereavement) a...

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Bibliographic Details
Published in:British journal of psychiatry 2012-12, Vol.201 (6), p.458-465
Main Authors: Hosang, Georgina M., Korszun, Ania, Jones, Lisa, Jones, Ian, McGuffin, Peter, Farmer, Anne E.
Format: Article
Language:English
Subjects:
Adult
Affective disorders
Bereavement
Bipolar affective disorder
Bipolar disorder
Bipolar Disorder - psychology
Case-Control Studies
Declarations
Depressive Disorder - psychology
Divorce
Economic crisis
Emotional disorders
Female
Humans
Inconsistency
Life Change Events
Life stress
Male
Mental depression
Middle Aged
Mood
Psychiatry
Psychopathology
Regression Analysis
Schizophrenia
Self help
Stress
Stress, Psychological - psychology
Stressful events
Support groups
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Summary:Little is known about the impact of different types of stressful events (for example divorce v. bereavement) on unipolar depression compared with bipolar disorder. Inconsistencies exist concerning the association between independent events (beyond an individual's control, such as bereavement) and bipolar disorder. To examine the role of specific, independent and dependent events in mood disorders. Life-event information was collected from 512 people with bipolar disorder, 1448 people with unipolar depression and over 600 controls. Various events were associated with unipolar depression and bipolar disorder, but some event specificity was detected. For example, financial crisis was more strongly related to bipolar disorder rather than unipolar depression. Independent events were only related to unipolar depression and not bipolar disorder. The events that were linked to bipolar disorder and unipolar depression were similar. Independent events were not associated with bipolar episodes, suggesting that life stress may be a consequence of, rather than a trigger for, bipolar episodes.
ISSN:0007-1250
1472-1465
DOI:10.1192/bjp.bp.112.111047