Predictors of Coronary Lesions Complexity in Patients With Stable Coronary Artery Disease

• Published in: Angiology 2013-05, Vol.64 (4), p.304-309
• Main Authors: Aksakal, Enbiya, Tanboga, Ibrahim Halil, Kurt, Mustafa, Kaya, Ahmet, Topcu, Selim, Kalkan, Kamuran, Sevimli, Serdar
• Format: Article
• Language: English
• Subjects: Aged; Angina, Stable - blood; Angina, Stable - diagnosis; Angina, Stable - epidemiology; Angina, Stable - physiopathology; Biomarkers - blood; C-Reactive Protein - analysis; Chi-Square Distribution; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Coronary Angiography; Coronary Artery Disease - blood; Coronary Artery Disease - diagnosis; Coronary Artery Disease - epidemiology; Coronary Artery Disease - physiopathology; Diabetes Mellitus - epidemiology; Female; Glomerular Filtration Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Kidney - physiopathology; Kidney Diseases - diagnosis; Kidney Diseases - epidemiology; Kidney Diseases - physiopathology; Logistic Models; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke Volume; Triglycerides - blood; Turkey - epidemiology; Ventricular Dysfunction, Left - diagnosis; Ventricular Dysfunction, Left - epidemiology; Ventricular Dysfunction, Left - physiopathology; Ventricular Function, Left
• ISSN: 0003-3197; 1940-1574
• DOI: 10.1177/0003319712464815

Only a few studies focused on the predictors of the SYNTAX score (SS). We evaluated the independent clinical predictors of SS in 436 consecutive patients with stable angina pectoris who underwent coronary angiography. Estimated glomerular filtration rate (eGFR) was calculated. The mean SS was 25.8 ± 13.7. High-sensitivity C-reactive protein and low-density lipoprotein cholesterol levels gradually rise while high-density lipoprotein cholesterol (HDL-C), triglycerides, and eGFR levels gradually decline from low to high SS tertile. Multivariate logistic regression analysis revealed that diabetes (P = .005), left ventricular ejection fraction ([LVEF]; P < .001), previous statin use (P = .02), HDL-C level (P < .001), and eGFR (P < .001) were independent predictors of SS. In conclusion, the presence of diabetes mellitus, no previous statin use, and lower values of HDL-C, LVEF, and eGFR were independent predictors of coronary heart disease complexity. This study has been accepted to present at the 28th Turkish National Cardiology Congress.