Oncological and functional outcomes after radical nephrectomy for renal cell carcinoma: A comprehensive analysis of prognostic factors

Objectives To investigate mortality rates and to comprehensively analyze prognostic indicators after radical nephrectomy for renal cell carcinoma. Methods Data were collected from 147 patients who underwent potentially curative radical nephrectomy for renal cell carcinoma. The following data were an...

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Bibliographic Details
Published in:International journal of urology 2013-04, Vol.20 (4), p.382-389
Main Authors: Sejima, Takehiro, Iwamoto, Hideto, Masago, Toshihiko, Morizane, Shuichi, Hinata, Nobuyuki, Yao, Akihisa, Isoyama, Tadahiro, Saito, Motoaki, Takenaka, Atsushi
Format: Article
Language:English
Subjects:
Adenocarcinoma, Clear Cell - mortality
Adenocarcinoma, Clear Cell - surgery
Adult
Aged
Aged, 80 and over
Carcinoma, Renal Cell - mortality
Carcinoma, Renal Cell - surgery
cardiovascular disease events
chronic kidney disease
Comorbidity
Female
Follow-Up Studies
Glomerular Filtration Rate
Humans
Hypertension, Renal - mortality
Kaplan-Meier Estimate
Kidney Neoplasms - mortality
Kidney Neoplasms - surgery
Male
Middle Aged
Multivariate Analysis
Nephrectomy - methods
Nephrectomy - mortality
Postoperative Complications - mortality
Prognosis
Proteinuria - mortality
radical nephrectomy
renal cell carcinoma
Risk Factors
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Summary:Objectives To investigate mortality rates and to comprehensively analyze prognostic indicators after radical nephrectomy for renal cell carcinoma. Methods Data were collected from 147 patients who underwent potentially curative radical nephrectomy for renal cell carcinoma. The following data were analyzed: tumor pathology, patient demographics and clinical parameters, such as pre‐ and postoperative estimated glomerular filtration rate, as well as the cause of death. Cause‐specific survival rates were calculated including deaths caused by renal cell carcinoma and cardiovascular disease. A Cox proportional hazard model was used for statistical analysis. Results A univariate analysis showed that age at surgery (≥70 years), postoperative estimated glomerular filtration rate (
ISSN:0919-8172
1442-2042
DOI:10.1111/j.1442-2042.2012.03176.x