Risk factors of choledocholithiasis formation after liver transplantation

Systematic study of risk factors for biliary stone post-liver transplantation is rarely performed. To investigate the risk factor of choledocholithiasis formation after liver transplantation, we c onducted a case-control study. Fourteen patients were selected into a study group. The stones of the bi...

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Bibliographic Details
Published in:Hepatobiliary & pancreatic diseases international 2013-04, Vol.12 (2), p.215-217
Main Authors: Yu, Zhi-Yong, Zhang, Min, Qin, Yun-Sheng, Zhou, Xiao-Ping, Cai, Ming-Yue, Yu, Song-Feng, Ke, Qing-Hong, Zheng, Shu-Sen
Format: Article
Language:English
Subjects:
bile
biliary
biliary tract diseases
Case-Control Studies
Chi-Square Distribution
cholangiopancreatography
Cholangiopancreatography, Endoscopic Retrograde
choledocholithiasis
Choledocholithiasis - diagnosis
Choledocholithiasis - etiology
Choledocholithiasis - surgery
Cholestasis - etiology
common
common bile duct stone
Constriction, Pathologic
diseases
duct
Endocrinology & Metabolism
endoscopic
endoscopic retrograde cholangiopancreatography
Female
gallstones
Gastroenterology and Hepatology
Humans
liver
liver transplantation
Liver Transplantation - adverse effects
Logistic Models
Male
Middle Aged
Multivariate Analysis
retrograde
Risk Assessment
Risk Factors
stone
tract
transplantation
Treatment Outcome
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Summary:Systematic study of risk factors for biliary stone post-liver transplantation is rarely performed. To investigate the risk factor of choledocholithiasis formation after liver transplantation, we c onducted a case-control study. Fourteen patients were selected into a study group. The stones of the bile duct of the patients were confirmed and treated successfully by endoscopic retrograde cholangiopancreatography. For univariate analysis, we selected carefully some potential risk factors such as cold ischemia time, warm ischemia time, and biliary stricture. The results revealed that cold ischemia time and biliary stenosis were significant predictors. But multivariate analysis revealed that only biliary stenosis was a significant risk factor. In conclusion, biliary stenosis is a risk factor of bile duct stones formation after liver transplantation. Endoscopic retrograde cholangiopancreatography is effective and safe in the diagnosis or treatment of bile duct stones after liver transplantation.
ISSN:1499-3872
DOI:10.1016/S1499-3872(13)60034-X