Postoperative survival of lung cancer patients: are there predictors beyond TNM?

We report on survival data of 595 patients with stage I-III lung cancer with respect to TNM classification. We constructed a basic model consisting of stage and grade, and assessed the improvement of survival prediction after adding comorbidity data, spirometric data, clinical and laboratory paramet...

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Bibliographic Details
Published in:Anticancer research 2013-04, Vol.33 (4), p.1609-1619
Main Authors: Friedel, Godehard, Fritz, Peter, Goletz, Sven, Kristen, Ralf, Brinkmann, Friedhelm, Dierkesmann, Rainer, Schwab, Matthias, Ott, German, Dippon, Jürgen, Alscher, Mark Dominik
Format: Article
Language:English
Subjects:
Adenocarcinoma - mortality
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Adenocarcinoma, Bronchiolo-Alveolar - mortality
Adenocarcinoma, Bronchiolo-Alveolar - pathology
Adenocarcinoma, Bronchiolo-Alveolar - surgery
Adult
Aged
Aged, 80 and over
Body Mass Index
Carcinoma, Non-Small-Cell Lung - mortality
Carcinoma, Non-Small-Cell Lung - pathology
Carcinoma, Non-Small-Cell Lung - surgery
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - surgery
Cardiovascular Diseases - etiology
Comorbidity
Creatinine - metabolism
Female
Humans
Lung Neoplasms - mortality
Lung Neoplasms - pathology
Lung Neoplasms - surgery
Male
Middle Aged
Neoplasm Staging
Oxygen - metabolism
Postoperative Complications
Prognosis
Proportional Hazards Models
Risk Factors
Small Cell Lung Carcinoma - mortality
Small Cell Lung Carcinoma - pathology
Small Cell Lung Carcinoma - surgery
Survival Rate
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Summary:We report on survival data of 595 patients with stage I-III lung cancer with respect to TNM classification. We constructed a basic model consisting of stage and grade, and assessed the improvement of survival prediction after adding comorbidity data, spirometric data, clinical and laboratory parameters. Body mass index (BMI) and presence of a cardiac disease reached statistical significance for prediction of overall survival in a Cox regression model. In addition to BMI (
ISSN:1791-7530