High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: Evidence for a role of the adenosinergic system

Highlights ► Exercise attenuates mechanical allodynia on complex regional pain syndrome type I. ► Caffeine reverses antiallodynic effect produced by high-intensity swimming exercise. ► Antiallodynic effect caused by exercise involves the activation of the A1 receptors.

Saved in:
Bibliographic Details
Published in:Neuroscience 2013-03, Vol.234, p.69-76
Main Authors: Martins, D.F, Mazzardo-Martins, L, Soldi, F, Stramosk, J, Piovezan, A.P, Santos, A.R.S
Format: Article
Language:English
Subjects:
Adenine - analogs & derivatives
adenosine
Adenosine - physiology
Adenosine A1 Receptor Antagonists - pharmacology
Adenosine A2 Receptor Antagonists - pharmacology
Adenosine Deaminase Inhibitors - pharmacology
analgesia
Animals
Biological and medical sciences
caffeine
Caffeine - pharmacology
CRPS-I
exercise
Exercise Therapy
Hyperalgesia - complications
Hyperalgesia - physiopathology
Hyperalgesia - therapy
Male
Medical sciences
Mice
Naloxone - pharmacology
Narcotic Antagonists - pharmacology
Nervous system involvement in other diseases. Miscellaneous
Neuralgia - complications
Neuralgia - therapy
Neurology
Neurons - drug effects
Neurons - physiology
Neuropharmacology
Pharmacology. Drug treatments
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Reflex Sympathetic Dystrophy - complications
Reflex Sympathetic Dystrophy - therapy
Swimming
Triazines - pharmacology
Triazoles - pharmacology
Xanthines - pharmacology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights ► Exercise attenuates mechanical allodynia on complex regional pain syndrome type I. ► Caffeine reverses antiallodynic effect produced by high-intensity swimming exercise. ► Antiallodynic effect caused by exercise involves the activation of the A1 receptors.
ISSN:0306-4522
1873-7544
DOI:10.1016/j.neuroscience.2012.12.042