Paraneoplastic extralimbic encephalitis associated with thymoma and myastenia gravis: Three years follow up

Approximately 10-15% of the patients have other PNS, like limbic encephalitis, neuromyotonia, peripheral neuropathy, inflammatory myopathy, subacute hearing loss, psychosis, sleep disorders and stiff-person syndrome. In one case, thymoma and ELE was accompanied with stiff-person syndrome [4]. Since...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2013-05, Vol.115 (5), p.628-631
Main Authors: Aysal, F, Baybas, S, Selçuk, H.H, Sozmen, V, Ozturk, M, Kucukoglu, H, Urer, N.H
Format: Article
Language:English
Subjects:
Anticonvulsants - therapeutic use
Aphasia
Autoimmune diseases
Cholinesterase Inhibitors - therapeutic use
Electroencephalography
Extralimbic encephalitis
Follow-Up Studies
Magnetic Resonance Imaging
Myastenia gravis
Myasthenia Gravis - complications
Neurology
Neurosurgery
Paraneoplastic
Paraneoplastic Syndromes, Nervous System - complications
Paraneoplastic Syndromes, Nervous System - diagnosis
Paraneoplastic Syndromes, Nervous System - drug therapy
Pathogenesis
Patients
Piracetam - analogs & derivatives
Piracetam - therapeutic use
Pyridostigmine Bromide - therapeutic use
Seizures - etiology
Thymectomy
Thymoma
Thymoma - complications
Thymus Neoplasms - complications
Tomography, X-Ray Computed
Treatment Outcome
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Description
Summary:Approximately 10-15% of the patients have other PNS, like limbic encephalitis, neuromyotonia, peripheral neuropathy, inflammatory myopathy, subacute hearing loss, psychosis, sleep disorders and stiff-person syndrome. In one case, thymoma and ELE was accompanied with stiff-person syndrome [4]. Since the symptoms are not specific, diagnosis in ELE related to thymoma is quite hard to detect.
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2012.06.016