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Low calorie and carbohydrate diet: to improve the cardiovascular risk indicators in overweight or obese adults with prediabetes

Our objective was to evaluate the effects of a moderate calorie and carbohydrate-restricted diet on cardiovascular risk indicators in overweight or obese patients with prediabetes. A clinical trial was conducted in which 86 subjects presenting with overweight or obesity and prediabetes received a pe...

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Published in:Endocrine 2013-06, Vol.43 (3), p.593-602
Main Authors: Velázquez-López, Lubia, González-Figueroa, Evangelina, Medina-Bravo, Patricia, Pineda-del Aguila, Ignacio, Ávila-Jiménez, Laura, Ramos-Hernández, Rosa, Klunder-Klunder, Miguel, Escobedo-de la Peña, Jorge
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creator Velázquez-López, Lubia
González-Figueroa, Evangelina
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Klunder-Klunder, Miguel
Escobedo-de la Peña, Jorge
description Our objective was to evaluate the effects of a moderate calorie and carbohydrate-restricted diet on cardiovascular risk indicators in overweight or obese patients with prediabetes. A clinical trial was conducted in which 86 subjects presenting with overweight or obesity and prediabetes received a personalized diet of 1,200 to 1,700 calories with a distribution of 50 % carbohydrates, 20 % proteins, and 30 % fat. Body weight, fat mass, and lean mass were measured through bioimpedance. Glucose, total cholesterol, high density lipoprotein cholesterol and low density cholesterol, and triglycerides were measured. The measurements were taken at the beginning of, and at, 6 and 12 months during the intervention, and the differences were compared by paired Student’s t and χ 2 tests. At 12 months, a significant reduction was noticed in body weight in patients with overweight and obesity (72.4 ± 7.8–69.6 ± 7.5 kg) (85.7 ± 14.8–80.2 ± 12.7 kg) with body mass index (28.2 ± 0.8–27.2 ± 2.1 kg/m 2 ) (34.3 ± 3.5–32.1 ± 3.2 kg/m 2 ), systolic (120.9 ± 14.2–112.4 ± 11.5 mmHg) (124.1 ± 11.9–115.7 ± 14.0 mmHg), diastolic blood pressures (79.0 ± 9.3–71.8 ± 8.3 mmHg) (80.4 ± 9.0–73.7 ± 13.1 mmHg), glucose (106.0 ± 8.9–95.9 ± 7.5 mg/dL) (107.3 ± 7.0–97.0 ± 8.2 mg/dL), and significant improvement on lipid profile ( p  
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ispartof Endocrine, 2013-06, Vol.43 (3), p.593-602
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1559-0100
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subjects Adult
Caloric Restriction
Cardiovascular Diseases - etiology
Cardiovascular Diseases - prevention & control
Diabetes
Diet, Carbohydrate-Restricted
Endocrinology
Female
Humanities and Social Sciences
Humans
Internal Medicine
Male
Medicine
Medicine & Public Health
Middle Aged
multidisciplinary
Obesity - complications
Obesity - diet therapy
Original Article
Overweight - complications
Overweight - diet therapy
Prediabetic State - complications
Prediabetic State - diet therapy
Risk Factors
Science
Treatment Outcome
Weight Loss
title Low calorie and carbohydrate diet: to improve the cardiovascular risk indicators in overweight or obese adults with prediabetes
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