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Low calorie and carbohydrate diet: to improve the cardiovascular risk indicators in overweight or obese adults with prediabetes
Our objective was to evaluate the effects of a moderate calorie and carbohydrate-restricted diet on cardiovascular risk indicators in overweight or obese patients with prediabetes. A clinical trial was conducted in which 86 subjects presenting with overweight or obesity and prediabetes received a pe...
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Published in: | Endocrine 2013-06, Vol.43 (3), p.593-602 |
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creator | Velázquez-López, Lubia González-Figueroa, Evangelina Medina-Bravo, Patricia Pineda-del Aguila, Ignacio Ávila-Jiménez, Laura Ramos-Hernández, Rosa Klunder-Klunder, Miguel Escobedo-de la Peña, Jorge |
description | Our objective was to evaluate the effects of a moderate calorie and carbohydrate-restricted diet on cardiovascular risk indicators in overweight or obese patients with prediabetes. A clinical trial was conducted in which 86 subjects presenting with overweight or obesity and prediabetes received a personalized diet of 1,200 to 1,700 calories with a distribution of 50 % carbohydrates, 20 % proteins, and 30 % fat. Body weight, fat mass, and lean mass were measured through bioimpedance. Glucose, total cholesterol, high density lipoprotein cholesterol and low density cholesterol, and triglycerides were measured. The measurements were taken at the beginning of, and at, 6 and 12 months during the intervention, and the differences were compared by paired Student’s
t
and χ
2
tests. At 12 months, a significant reduction was noticed in body weight in patients with overweight and obesity (72.4 ± 7.8–69.6 ± 7.5 kg) (85.7 ± 14.8–80.2 ± 12.7 kg) with body mass index (28.2 ± 0.8–27.2 ± 2.1 kg/m
2
) (34.3 ± 3.5–32.1 ± 3.2 kg/m
2
), systolic (120.9 ± 14.2–112.4 ± 11.5 mmHg) (124.1 ± 11.9–115.7 ± 14.0 mmHg), diastolic blood pressures (79.0 ± 9.3–71.8 ± 8.3 mmHg) (80.4 ± 9.0–73.7 ± 13.1 mmHg), glucose (106.0 ± 8.9–95.9 ± 7.5 mg/dL) (107.3 ± 7.0–97.0 ± 8.2 mg/dL), and significant improvement on lipid profile (
p
|
doi_str_mv | 10.1007/s12020-012-9775-z |
format | article |
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t
and χ
2
tests. At 12 months, a significant reduction was noticed in body weight in patients with overweight and obesity (72.4 ± 7.8–69.6 ± 7.5 kg) (85.7 ± 14.8–80.2 ± 12.7 kg) with body mass index (28.2 ± 0.8–27.2 ± 2.1 kg/m
2
) (34.3 ± 3.5–32.1 ± 3.2 kg/m
2
), systolic (120.9 ± 14.2–112.4 ± 11.5 mmHg) (124.1 ± 11.9–115.7 ± 14.0 mmHg), diastolic blood pressures (79.0 ± 9.3–71.8 ± 8.3 mmHg) (80.4 ± 9.0–73.7 ± 13.1 mmHg), glucose (106.0 ± 8.9–95.9 ± 7.5 mg/dL) (107.3 ± 7.0–97.0 ± 8.2 mg/dL), and significant improvement on lipid profile (
p
< 0.05). The restrictions in the calorie and carbohydrate diet decrease the cardiovascular risk indicators in overweight or obese adults with prediabetes.</description><identifier>ISSN: 1355-008X</identifier><identifier>EISSN: 1559-0100</identifier><identifier>DOI: 10.1007/s12020-012-9775-z</identifier><identifier>PMID: 22941424</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Adult ; Caloric Restriction ; Cardiovascular Diseases - etiology ; Cardiovascular Diseases - prevention & control ; Diabetes ; Diet, Carbohydrate-Restricted ; Endocrinology ; Female ; Humanities and Social Sciences ; Humans ; Internal Medicine ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; multidisciplinary ; Obesity - complications ; Obesity - diet therapy ; Original Article ; Overweight - complications ; Overweight - diet therapy ; Prediabetic State - complications ; Prediabetic State - diet therapy ; Risk Factors ; Science ; Treatment Outcome ; Weight Loss</subject><ispartof>Endocrine, 2013-06, Vol.43 (3), p.593-602</ispartof><rights>Springer Science+Business Media, LLC 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c344t-bb4e611473bf5c7f58678132621e48bbf9f25d23bbf1138866a82689466182e93</citedby><cites>FETCH-LOGICAL-c344t-bb4e611473bf5c7f58678132621e48bbf9f25d23bbf1138866a82689466182e93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22941424$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Velázquez-López, Lubia</creatorcontrib><creatorcontrib>González-Figueroa, Evangelina</creatorcontrib><creatorcontrib>Medina-Bravo, Patricia</creatorcontrib><creatorcontrib>Pineda-del Aguila, Ignacio</creatorcontrib><creatorcontrib>Ávila-Jiménez, Laura</creatorcontrib><creatorcontrib>Ramos-Hernández, Rosa</creatorcontrib><creatorcontrib>Klunder-Klunder, Miguel</creatorcontrib><creatorcontrib>Escobedo-de la Peña, Jorge</creatorcontrib><title>Low calorie and carbohydrate diet: to improve the cardiovascular risk indicators in overweight or obese adults with prediabetes</title><title>Endocrine</title><addtitle>Endocrine</addtitle><addtitle>Endocrine</addtitle><description>Our objective was to evaluate the effects of a moderate calorie and carbohydrate-restricted diet on cardiovascular risk indicators in overweight or obese patients with prediabetes. A clinical trial was conducted in which 86 subjects presenting with overweight or obesity and prediabetes received a personalized diet of 1,200 to 1,700 calories with a distribution of 50 % carbohydrates, 20 % proteins, and 30 % fat. Body weight, fat mass, and lean mass were measured through bioimpedance. Glucose, total cholesterol, high density lipoprotein cholesterol and low density cholesterol, and triglycerides were measured. The measurements were taken at the beginning of, and at, 6 and 12 months during the intervention, and the differences were compared by paired Student’s
t
and χ
2
tests. At 12 months, a significant reduction was noticed in body weight in patients with overweight and obesity (72.4 ± 7.8–69.6 ± 7.5 kg) (85.7 ± 14.8–80.2 ± 12.7 kg) with body mass index (28.2 ± 0.8–27.2 ± 2.1 kg/m
2
) (34.3 ± 3.5–32.1 ± 3.2 kg/m
2
), systolic (120.9 ± 14.2–112.4 ± 11.5 mmHg) (124.1 ± 11.9–115.7 ± 14.0 mmHg), diastolic blood pressures (79.0 ± 9.3–71.8 ± 8.3 mmHg) (80.4 ± 9.0–73.7 ± 13.1 mmHg), glucose (106.0 ± 8.9–95.9 ± 7.5 mg/dL) (107.3 ± 7.0–97.0 ± 8.2 mg/dL), and significant improvement on lipid profile (
p
< 0.05). The restrictions in the calorie and carbohydrate diet decrease the cardiovascular risk indicators in overweight or obese adults with prediabetes.</description><subject>Adult</subject><subject>Caloric Restriction</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Cardiovascular Diseases - prevention & control</subject><subject>Diabetes</subject><subject>Diet, Carbohydrate-Restricted</subject><subject>Endocrinology</subject><subject>Female</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>multidisciplinary</subject><subject>Obesity - complications</subject><subject>Obesity - diet therapy</subject><subject>Original Article</subject><subject>Overweight - complications</subject><subject>Overweight - diet therapy</subject><subject>Prediabetic State - complications</subject><subject>Prediabetic State - diet therapy</subject><subject>Risk Factors</subject><subject>Science</subject><subject>Treatment Outcome</subject><subject>Weight Loss</subject><issn>1355-008X</issn><issn>1559-0100</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNp9kD1vFDEQhi0EIh_wA2gilzSb2LO210uHogQinUQDEp1lr2dzTvbWh-3NKWn46_h0IWUqv_I880jzEvKJs3POWHeROTBgDePQ9F0nm6c35JhL2dcfxt7W3ErZMKZ_H5GTnO8YAwDVvSdHAL3gAsQx-buKOzrYKaaA1M6-5uTi-tEnW5D6gOULLZGGzTbFB6RljXvCh_hg87BMNtEU8j0Nsw-DLTHlGmkl0w7D7brQmGh0mKvbL1PJdBfKmm4T-mAdFswfyLvRThk_Pr-n5Nf11c_L783qx7eby6-rZmiFKI1zAhXnomvdKIdulFp1mreggKPQzo39CNJDWxPnrdZKWQ1K90IprgH79pR8PnjrHX8WzMVsQh5wmuyMccmGt0LJqoSuovyADinmnHA02xQ2Nj0azsy-d3Po3dTezb5381R3zp71i9ugf9n4X3QF4ADkOppvMZm7uKS5nvyK9R-WZY_b</recordid><startdate>20130601</startdate><enddate>20130601</enddate><creator>Velázquez-López, Lubia</creator><creator>González-Figueroa, Evangelina</creator><creator>Medina-Bravo, Patricia</creator><creator>Pineda-del Aguila, Ignacio</creator><creator>Ávila-Jiménez, Laura</creator><creator>Ramos-Hernández, Rosa</creator><creator>Klunder-Klunder, Miguel</creator><creator>Escobedo-de la Peña, Jorge</creator><general>Springer US</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130601</creationdate><title>Low calorie and carbohydrate diet: to improve the cardiovascular risk indicators in overweight or obese adults with prediabetes</title><author>Velázquez-López, Lubia ; González-Figueroa, Evangelina ; Medina-Bravo, Patricia ; Pineda-del Aguila, Ignacio ; Ávila-Jiménez, Laura ; Ramos-Hernández, Rosa ; Klunder-Klunder, Miguel ; Escobedo-de la Peña, Jorge</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c344t-bb4e611473bf5c7f58678132621e48bbf9f25d23bbf1138866a82689466182e93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Caloric Restriction</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Cardiovascular Diseases - prevention & control</topic><topic>Diabetes</topic><topic>Diet, Carbohydrate-Restricted</topic><topic>Endocrinology</topic><topic>Female</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>multidisciplinary</topic><topic>Obesity - complications</topic><topic>Obesity - diet therapy</topic><topic>Original Article</topic><topic>Overweight - complications</topic><topic>Overweight - diet therapy</topic><topic>Prediabetic State - complications</topic><topic>Prediabetic State - diet therapy</topic><topic>Risk Factors</topic><topic>Science</topic><topic>Treatment Outcome</topic><topic>Weight Loss</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Velázquez-López, Lubia</creatorcontrib><creatorcontrib>González-Figueroa, Evangelina</creatorcontrib><creatorcontrib>Medina-Bravo, Patricia</creatorcontrib><creatorcontrib>Pineda-del Aguila, Ignacio</creatorcontrib><creatorcontrib>Ávila-Jiménez, Laura</creatorcontrib><creatorcontrib>Ramos-Hernández, Rosa</creatorcontrib><creatorcontrib>Klunder-Klunder, Miguel</creatorcontrib><creatorcontrib>Escobedo-de la Peña, Jorge</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Endocrine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Velázquez-López, Lubia</au><au>González-Figueroa, Evangelina</au><au>Medina-Bravo, Patricia</au><au>Pineda-del Aguila, Ignacio</au><au>Ávila-Jiménez, Laura</au><au>Ramos-Hernández, Rosa</au><au>Klunder-Klunder, Miguel</au><au>Escobedo-de la Peña, Jorge</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Low calorie and carbohydrate diet: to improve the cardiovascular risk indicators in overweight or obese adults with prediabetes</atitle><jtitle>Endocrine</jtitle><stitle>Endocrine</stitle><addtitle>Endocrine</addtitle><date>2013-06-01</date><risdate>2013</risdate><volume>43</volume><issue>3</issue><spage>593</spage><epage>602</epage><pages>593-602</pages><issn>1355-008X</issn><eissn>1559-0100</eissn><abstract>Our objective was to evaluate the effects of a moderate calorie and carbohydrate-restricted diet on cardiovascular risk indicators in overweight or obese patients with prediabetes. A clinical trial was conducted in which 86 subjects presenting with overweight or obesity and prediabetes received a personalized diet of 1,200 to 1,700 calories with a distribution of 50 % carbohydrates, 20 % proteins, and 30 % fat. Body weight, fat mass, and lean mass were measured through bioimpedance. Glucose, total cholesterol, high density lipoprotein cholesterol and low density cholesterol, and triglycerides were measured. The measurements were taken at the beginning of, and at, 6 and 12 months during the intervention, and the differences were compared by paired Student’s
t
and χ
2
tests. At 12 months, a significant reduction was noticed in body weight in patients with overweight and obesity (72.4 ± 7.8–69.6 ± 7.5 kg) (85.7 ± 14.8–80.2 ± 12.7 kg) with body mass index (28.2 ± 0.8–27.2 ± 2.1 kg/m
2
) (34.3 ± 3.5–32.1 ± 3.2 kg/m
2
), systolic (120.9 ± 14.2–112.4 ± 11.5 mmHg) (124.1 ± 11.9–115.7 ± 14.0 mmHg), diastolic blood pressures (79.0 ± 9.3–71.8 ± 8.3 mmHg) (80.4 ± 9.0–73.7 ± 13.1 mmHg), glucose (106.0 ± 8.9–95.9 ± 7.5 mg/dL) (107.3 ± 7.0–97.0 ± 8.2 mg/dL), and significant improvement on lipid profile (
p
< 0.05). The restrictions in the calorie and carbohydrate diet decrease the cardiovascular risk indicators in overweight or obese adults with prediabetes.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>22941424</pmid><doi>10.1007/s12020-012-9775-z</doi><tpages>10</tpages></addata></record> |
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subjects | Adult Caloric Restriction Cardiovascular Diseases - etiology Cardiovascular Diseases - prevention & control Diabetes Diet, Carbohydrate-Restricted Endocrinology Female Humanities and Social Sciences Humans Internal Medicine Male Medicine Medicine & Public Health Middle Aged multidisciplinary Obesity - complications Obesity - diet therapy Original Article Overweight - complications Overweight - diet therapy Prediabetic State - complications Prediabetic State - diet therapy Risk Factors Science Treatment Outcome Weight Loss |
title | Low calorie and carbohydrate diet: to improve the cardiovascular risk indicators in overweight or obese adults with prediabetes |
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