Adenosine-based molecular beacons as light-up probes for sensing heparin in plasma

This study presents an adenosine-based molecular beacon (MB) for the selective and sensitive detection of heparin based on the competitive binding between heparin and the MB stem to coralyne.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2013-05, Vol.49 (41), p.4607-4609
Main Authors: Kuo, Chia-Yin, Tseng, Wei-Lung
Format: Article
Language:English
Subjects:
Adenosine - chemistry
Berberine Alkaloids - chemistry
Heparin - blood
Humans
Hydrogen-Ion Concentration
Oligonucleotide Probes - chemistry
Spectrometry, Fluorescence
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Description
Summary:This study presents an adenosine-based molecular beacon (MB) for the selective and sensitive detection of heparin based on the competitive binding between heparin and the MB stem to coralyne.
ISSN:1359-7345
1364-548X
DOI:10.1039/c3cc40976g