Efficacy and safety of radiofrequency ablation for hepatocellular carcinoma in the caudate lobe of the liver

Aim Radiofrequency ablation (RFA) is a promising alternative to hepatic resection for the treatment of hepatocellular carcinoma (HCC) located in the caudate lobe. We evaluated the therapeutic efficacy and safety of RFA for HCC located in the caudate lobe compared with HCC located elsewhere in the li...

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Bibliographic Details
Published in:Hepatology research 2013-05, Vol.43 (5), p.467-474
Main Authors: Nishigaki, Youichi, Tomita, Eiichi, Hayashi, Hideki, Suzuki, Yusuke, Iritani, Soichi, Kato, Tomohiro, Yamada, Tetsuya
Format: Article
Language:English
Subjects:
caudate lobe
hepatocellular carcinoma
radiofrequency ablation
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Summary:Aim Radiofrequency ablation (RFA) is a promising alternative to hepatic resection for the treatment of hepatocellular carcinoma (HCC) located in the caudate lobe. We evaluated the therapeutic efficacy and safety of RFA for HCC located in the caudate lobe compared with HCC located elsewhere in the liver. Methods Overall, 555 consecutive patients treated by RFA for a single HCC tumor of less than 3 cm diameter, were enrolled in this study, including 20 patients with HCC located in the caudate lobe. Among these 20 patients, HCC was located in the Spiegel lobe in eight patients, in the paracaval portion in another 10 and in the caudate process in two. We evaluated differences in the local recurrence rate and the incidence of complications associated with RFA between the caudate and the non‐caudate groups. Results The 4‐year cumulative local recurrence rate after RFA in the caudate group and the non‐caudate group was 22.3% and 4.5%, respectively (P 
ISSN:1386-6346
1872-034X
DOI:10.1111/j.1872-034X.2012.01095.x