Compliance with antimalarial chemoprophylaxis in German soldiers: a 6-year survey

• Published in: Infection 2013-04, Vol.41 (2), p.311-320
• Main Authors: Frickmann, H., Schwarz, N. G., Holtherm, H.-U., Maaßen, W., Vorderwülbecke, F., Erkens, K., Fischer, M., Morwinsky, T., Hagen, R. M.
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Animals; Antimalarials - therapeutic use; Aquatic insects; Chemoprevention; Clinical and Epidemiological Study; Family Medicine; Female; General Practice; Germany, West; Health Knowledge, Attitudes, Practice; Humans; Infectious Diseases; Insect Bites and Stings - prevention & control; Internal Medicine; Malaria; Malaria - drug therapy; Malaria - prevention & control; Male; Medicine; Medicine & Public Health; Military Personnel - statistics & numerical data; Mosquito Nets; Mosquitoes; Patient Compliance - statistics & numerical data; Protective Clothing; Repellents; Risk assessment; Surveys and Questionnaires; Vector-borne diseases; Young Adult
• ISSN: 0300-8126; 1439-0973
• DOI: 10.1007/s15010-013-0411-5

Purpose Since 1992, German soldiers have been deployed in areas where malaria is endemic. Antimalarial chemoprophylaxis (CP) is directed according to the assessed risk and is provided free of charge. Compliance is crucial if its effect is to be reliable. This study analysed compliance with directed CP in German soldiers as well as its determinants. Methods Between 2003 and 2009, standardized questionnaire-based interviews were performed with 2,149 out of approximately 100,000 German soldiers who were deployed during this period in areas where malaria is endemic. The questionnaires dealt with information that the soldiers had received about malaria prior to their missions, with their adherence to mosquito-protective and antimalarial chemoprophylactic procedures, and their estimations of their individual level of exposure. Results About 1,308 out of 2,149 interviewed soldiers had been ordered to take CP, allowing for an assessment of the outcome parameter “CP-compliance”. About 76.9 % out of 1,308 soldiers to whom regular CP was directed took it regularly. The exposure variables “age”, “satisfaction with malaria counselling”, “perceived threat due to insects or mosquitoes” and “use of insect repellents” were positively associated with compliance with directed antimalarial CP. Conclusions The study confirms the findings of the French and US armies that even free-of-charge access to antimalarial medication will not lead to 100 % acceptance. The compliance problem is aggravated by the generally low age of deployed soldiers. Adequate counselling is crucial to increase adherence to antimalarial CP.