Chromatography in characterization of polysaccharides from medicinal plants and fungi

Polysaccharides isolated from medicinal plants and fungi exhibit multiple pharmacological activities. The biological activities of polysaccharides depend on their chemical characteristics. However, characterization of polysaccahrides is a challenge because of their complicated structure and macromol...

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Bibliographic Details
Published in:Journal of separation science 2013-01, Vol.36 (1), p.1-19
Main Authors: Hu, De-jun, Cheong, Kit-leong, Zhao, Jing, Li, Shao-ping
Format: Article
Language:English
Subjects:
Biochemistry
Biological and medical sciences
Characterization
Chromatography
Chromatography, High Pressure Liquid
Fungi
Fungi - chemistry
General pharmacology
Herbal medicine
Medical sciences
Medicinal fungus
Medicinal plants
Molecular Weight
Pharmacognosy. Homeopathy. Health food
Pharmacology
Pharmacology. Drug treatments
Plants, Medicinal - chemistry
Polysaccharides
Polysaccharides - chemistry
Polysaccharides - isolation & purification
Quality control
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Summary:Polysaccharides isolated from medicinal plants and fungi exhibit multiple pharmacological activities. The biological activities of polysaccharides depend on their chemical characteristics. However, characterization of polysaccahrides is a challenge because of their complicated structure and macromolecular mass. In this review, chromatography in characterization of polysaccharides, including physicochemical characterization (purity, molecular mass, and distribution), structural characterization (constituent monosaccharide composition and the ratio, the features of glycosidic linkages), and fingerprint of polysaccharides (acidic and enzymatic hydrolysates), from medicinal plants and fungi were reviewed and discussed according to the publications collected in Web of Science since 2007. The perspective for characterization of polysaccharides has also been described.
ISSN:1615-9306
1615-9314
DOI:10.1002/jssc.201200874