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Intrathecal application of short interfering RNA knocks down c-jun expression and augments spinal motoneuron death after root avulsion in adult rats

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Bibliographic Details
Published in:	Neuroscience 2013-06, Vol.241, p.268-279
Main Authors:	Cheng, X, Fu, R, Gao, M, Liu, S, Li, Y.-Q, Song, F.-H, Bruce, I.C, Zhou, L.-H, Wu, W
Format:	Article
Language:	English
Subjects:	Aging Animals Biological and medical sciences Blotting, Western c-jun Cell Death - physiology Flow Cytometry Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology Gene Knockdown Techniques gene silencing Genes, jun - physiology Immunohistochemistry Injections, Spinal Male motoneurons Motor Neurons - metabolism Motor Neurons - pathology Neurology PC12 Cells Radiculopathy - metabolism Radiculopathy - pathology Rats Rats, Sprague-Dawley regeneration Reverse Transcriptase Polymerase Chain Reaction RNA interference RNA, Small Interfering - administration & dosage root avulsion Spinal Cord - metabolism Spinal Cord - pathology Transfection Vertebrates: nervous system and sense organs
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