The influence of the location of the lesion on the absolute risk of the development of skin cancer in a patient with actinic keratosis

The objective of this paper is to answer the clinical question whether the location of the lesion in an individual patient with actinic keratosis (AK) influences the absolute risk of the development of skin cancer. Between 0.025% and 16% of AK lesions advance towards squamous cell carcinoma per year...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the European Academy of Dermatology and Venereology 2013-06, Vol.27 (6), p.667-671
Main Authors: Smit, P., Plomp, E., Neumann, H.A.M., Thio, H.B.
Format: Article
Language:English
Subjects:
Aged
Humans
Keratosis, Actinic - complications
Keratosis, Actinic - pathology
Male
Risk
Skin Neoplasms - epidemiology
Skin Neoplasms - etiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The objective of this paper is to answer the clinical question whether the location of the lesion in an individual patient with actinic keratosis (AK) influences the absolute risk of the development of skin cancer. Between 0.025% and 16% of AK lesions advance towards squamous cell carcinoma per year. It is not well known whether this risk differs between locations on the body. A systematic search of available literature resulted in seven articles of which the two highest scoring on relevance and validity were selected. These two studies indicate that the absolute risk on the development of skin cancer in patients with AK differs between locations of the lesion and that time to progression from AK to squamous cell carcinoma is not different among the locations of the lesions. However, both studies have very limited sample sizes.
ISSN:0926-9959
1468-3083
DOI:10.1111/jdv.12008