Reversible CT perfusion abnormalities in patient with migraine variant: A two phase process

Noninvasive perfusion techniques allow identifying areas of acute cerebral ischemia and infarction to assist in determination of the need for thrombolysis with tissue plasminogen activator (t-Pa). Studies have revealed that familial hemiplegic migraine 1R192Q mutations enhanced calcium influx and re...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2013-06, Vol.115 (6), p.830-832
Main Authors: Shah, Laxmi, Rana, Sandeep, Valeriano, James, Scott, Thomas F
Format: Article
Language:English
Subjects:
Anti-Inflammatory Agents - therapeutic use
Aphasia
Aphasia - etiology
Blood Volume - physiology
Cerebral Angiography
Cerebrovascular Circulation - physiology
Cortical spreading depression
CT perfusion
Dexamethasone - therapeutic use
Electroencephalography
Encephalitis
Family medical history
Female
Fever
GABA Agents - therapeutic use
Hemiplegia - etiology
Hospitalization
Humans
Magnetic Resonance Angiography
Magnetic Resonance Imaging
Medical imaging
Migraine
Migraine aura
Migraine Disorders - diagnostic imaging
Migraine Disorders - physiopathology
Migraine variant
Mutation
Neurology
Neurosurgery
Perfusion
Stroke
Tomography, X-Ray Computed
Valproic Acid - therapeutic use
Young Adult
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Summary:Noninvasive perfusion techniques allow identifying areas of acute cerebral ischemia and infarction to assist in determination of the need for thrombolysis with tissue plasminogen activator (t-Pa). Studies have revealed that familial hemiplegic migraine 1R192Q mutations enhanced calcium influx and reduced the threshold for stimulating cortical spreading depression greater in reproductive females. 4 Conclusion We present a patient with a two phase process of CBF abnormalities seen on perfusion CT, corresponding to the development and eventual resolution of prominent stroke like symptoms in a patient with a history of prior hemiplegic migraine.
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2012.08.012