Detection of Epstein-Barr Virus and Genotyping Based on EBNA2 Protein in Mexican Patients With Hodgkin Lymphoma: A Comparative Study in Children and Adults

Micro-Abstract The frequency of Epstein-Barr virus (EBV) and the distribution of EBNA genotypes in children and adults with Hodgkin lymphoma (HL) in Mexico were analyzed. The frequency of EBV infection in patients previously diagnosed with lymphoma was high, was found most frequently in children rat...

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Published in:Clinical lymphoma, myeloma and leukemia myeloma and leukemia, 2013-06, Vol.13 (3), p.266-272
Main Authors: Palma, Icela, Sánchez, Ana Elena, Jiménez-Hernández, Elva, Alvarez-Rodríguez, Francisco, Nava-Frias, Margarita, Valencia-Mayoral, Pedro, Salinas-Lara, Citlatepet, Velazquez-Guadarrama, Norma, Portilla-Aguilar, Josefina, Pena, Rocio Y, Ramos-Salazar, Patricia, Contreras, Alejandra, Alfaro, Ana, Espinosa, Ana Maria, Nájera, Nayelli, Gutierrez, Gisela, Mejia-Arangure, Juan Manuel, Arellano-Galindo, José
Format: Article
Language:English
Subjects:
Adolescent
Adult
Child
Child, Preschool
DNA
EBER
EBNA2A
EBNA2B
Epstein-Barr virus
Epstein-Barr Virus Infections - pathology
Epstein-Barr Virus Infections - virology
Epstein-Barr Virus Nuclear Antigens - genetics
Female
Genotype
Hematology, Oncology and Palliative Medicine
Herpesvirus 4, Human - genetics
Herpesvirus 4, Human - immunology
Herpesvirus 4, Human - isolation & purification
Hodgkin Disease - pathology
Hodgkin Disease - virology
Humans
Immunohistochemistry
In Situ Hybridization
LMP
Male
Retrospective Studies
Viral Proteins - genetics
Young Adult
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Summary:Micro-Abstract The frequency of Epstein-Barr virus (EBV) and the distribution of EBNA genotypes in children and adults with Hodgkin lymphoma (HL) in Mexico were analyzed. The frequency of EBV infection in patients previously diagnosed with lymphoma was high, was found most frequently in children rather than adults, and was more frequent in male patients than in female patients. EBNA2B was the most frequent genotype.
ISSN:2152-2650
2152-2669
DOI:10.1016/j.clml.2012.11.010