A Case of Rhabdomyolysis in the Presence of Multiple Risk Factors and Dextroamphetamine Use

Abstract A 44-year-old Caucasian woman presented to the emergency room with worsening low back pain and loss of cutaneous sensation over the paraspinal muscles from T10 to S1. The patient had ingested the attention-deficit disorder medication dextroamphetamine before engaging in intense physical exe...

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Bibliographic Details
Published in:The American journal of the medical sciences 2013-06, Vol.345 (6), p.494-496
Main Authors: Santoro, Jonathan D., MD, Black, Jeanette M., MD, Lee Hamm, L., MD
Format: Article
Language:English
Subjects:
Adult
Alcohol Drinking - adverse effects
Amphetamine
Attention Deficit Disorder with Hyperactivity - drug therapy
Attention-deficit disorder
Back Pain - diagnosis
Back Pain - etiology
Central Nervous System Stimulants - adverse effects
Central Nervous System Stimulants - therapeutic use
Dextroamphetamine
Dextroamphetamine - adverse effects
Dextroamphetamine - therapeutic use
Exercise
Female
Humans
Internal Medicine
Plant Preparations - adverse effects
Rhabdomyolysis
Rhabdomyolysis - diagnosis
Rhabdomyolysis - etiology
Risk Factors
Stimulants
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Summary:Abstract A 44-year-old Caucasian woman presented to the emergency room with worsening low back pain and loss of cutaneous sensation over the paraspinal muscles from T10 to S1. The patient had ingested the attention-deficit disorder medication dextroamphetamine before engaging in intense physical exercise with subsequent consumption of 3 alcoholic beverages before developing symptoms. The patient’s creatine kinase levels remained elevated for 8 days with constant severe pain under standard treatment for rhabdomyolysis. Despite stabilization of pain and laboratory values at discharge, the patient continues to experience low paraspinal back pain. In patients with risk factors for rhabdomyolysis, the use of dextroamphetamine should be monitored closely. Outside our findings, there is no literature linking dextroamphetamine with rhabdomyolysis at nontoxic concentrations or with use of the supplement caffeine containing weight loss supplement, Hydroxycut. The authors believe that further research into the potential role of dextroamphetamine use in the setting of other risk factors for rhabdomyolysis is warranted.
ISSN:0002-9629
1538-2990
DOI:10.1097/MAJ.0b013e3182798040