Features of systemic lupus erythematosus in patients with autoimmune hepatitis

Although systemic lupus erythematosus (SLE) and autoimmune hepatitis (AIH) are distinct diseases, in clinical practice differentiation of one from other may be difficult. The aim of this study was to asses features of SLE in patients with diagnosis of AIH.Thirty patients [mean age: 52.4 ± 11.8 years...

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Bibliographic Details
Published in:Rheumatology international 2013-06, Vol.33 (6), p.1581-1585
Main Authors: Önder, Fatih Ouz, Yürekli, Öykü Tayfur, Öztas, Erkin, Kalkan, Ismail Hakki, Köksal, Aydin Seref, Akdoan, Meral, Sasmaz, Nurgül, Kayaçetin, Erturul
Format: Article
Language:English
Subjects:
Adult
Aged
Alanine Transaminase - blood
Biopsy
Female
Hepatitis, Autoimmune - complications
Hepatitis, Autoimmune - pathology
Hepatitis, Autoimmune - physiopathology
Humans
Liver - pathology
Lupus Erythematosus, Systemic - complications
Lupus Erythematosus, Systemic - pathology
Lupus Erythematosus, Systemic - physiopathology
Male
Medicine & Public Health
Middle Aged
Original Article
Rheumatology
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Summary:Although systemic lupus erythematosus (SLE) and autoimmune hepatitis (AIH) are distinct diseases, in clinical practice differentiation of one from other may be difficult. The aim of this study was to asses features of SLE in patients with diagnosis of AIH.Thirty patients [mean age: 52.4 ± 11.8 years; 23 (76.7 %) female] were included in the study. Seven (23.3 %) of the patients full filled 4 or more criteria for classification of SLE. None of the patients had muco-cutaneous lesions characteristic to SLE. Three patients had rheumatoid factor negative arthritis, and 2 patients had pericardial effusion. Four patients had significant thrombocytopenia (
ISSN:0172-8172
1437-160X
DOI:10.1007/s00296-012-2607-x