Bupropion pre-treatment of endotoxin-induced depressive symptoms

Highlight ► Bupropion pre-treatment has minimal effect on LPS-induced depressive symptoms and no effect on LPS-induced cytokines and chemokines.

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Bibliographic Details
Published in:Brain, behavior, and immunity behavior, and immunity, 2013-07, Vol.31, p.197-204
Main Authors: DellaGioia, Nicole, Devine, Lesley, Pittman, Brian, Hannestad, Jonas
Format: Article
Language:English
Subjects:
Adult
Allergy and Immunology
Antidepressant
Antidepressive Agents, Second-Generation - therapeutic use
Blood Pressure
Bupropion
Bupropion - therapeutic use
Chemokines
Chemokines - blood
Cross-Over Studies
Cytokines
Cytokines - blood
Depression
Depression - blood
Depression - chemically induced
Depression - diagnosis
Depression - drug therapy
Double-Blind Method
Endotoxin
Fatigue
Female
Heart Rate
Humans
Lipopolysaccharides
Male
Psychiatry
Treatment Outcome
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Description
Summary:Highlight ► Bupropion pre-treatment has minimal effect on LPS-induced depressive symptoms and no effect on LPS-induced cytokines and chemokines.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2012.10.008