Do lymphocytes from Chagasic patients respond to heart antigens?

Trypanosoma cruzi, lymphocytes from chronic Chagasic patients, blastogenic responses to various antigenic preparations (including epimastigote supernatant, human heart homogenate, mouse heart homogenate, streptococcal enzymes), results suggest possibility that positive lymphocyte transformation to u...

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Bibliographic Details
Published in:Infection and Immunity 1983-05, Vol.40 (2), p.832-835
Main Authors: Todd, C.W, Todd, N.R, Guimaraes, A.C
Format: Article
Language:English
Subjects:
Adult
Antigens - immunology
cell-mediated immunity
Chagas Disease - immunology
heart
Humans
Immunity, Autoimmunity
Immunity, Cellular
immunopathology
Lymphocyte Activation
lymphocytes
Lymphocytes - immunology
Middle Aged
Myocardium - immunology
Streptococcus - immunology
Trypanosoma cruzi
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Summary:Trypanosoma cruzi, lymphocytes from chronic Chagasic patients, blastogenic responses to various antigenic preparations (including epimastigote supernatant, human heart homogenate, mouse heart homogenate, streptococcal enzymes), results suggest possibility that positive lymphocyte transformation to unfractionated heart antigen preparations may not represent specific reactivity to heart antigens
ISSN:0019-9567
1098-5522
DOI:10.1128/IAI.40.2.832-835.1983