Psychomimetic reactions after low-dose ketamine infusion. Comparison with neuroleptanaesthesia

Low-dose ketamine anaesthesia was compared with neuroleptanaesthesia, in respect of immediate and longer-term psychomimetic reactions, in 40 female patients undergoing elective gynaecological surgery. Qualitatively, but not quantitatively, different psychomimetic reactions occurred in both groups. I...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1983-04, Vol.55 (4), p.297-302
Main Authors: Klausen, N O, Wiberg-Jørgensen, F, Chraemmer-Jørgensen, B
Format: Article
Language:English
Subjects:
Adult
Anesthesia, Intravenous - adverse effects
Attention - drug effects
Dreams - drug effects
Drug Administration Schedule
Female
Hallucinations - chemically induced
Humans
Illusions - drug effects
Ketamine - administration & dosage
Ketamine - adverse effects
Memory - drug effects
Middle Aged
Neuroleptanalgesia - adverse effects
Patient Acceptance of Health Care
Time Factors
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Summary:Low-dose ketamine anaesthesia was compared with neuroleptanaesthesia, in respect of immediate and longer-term psychomimetic reactions, in 40 female patients undergoing elective gynaecological surgery. Qualitatively, but not quantitatively, different psychomimetic reactions occurred in both groups. In the neurolept group the predominant complaint was of a dissociative nature, reported after 24 h by 11 (55%) of the patients, while in the ketamine group the predominant experience was dreaming, reported by eight (40%) of the patients after 24 h. Interviews after 3 months revealed a low frequency of psychomimetic reactions in both groups. However, 30% of all the patients (12) complained of impairment of intellectual function, and in seven patients this was severe enough to interfere with their ability to work.
ISSN:0007-0912