Preliminary evaluation of tear production in dogs hospitalized in an intensive care unit

• Published in: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2000) Tex. : 2000), 2013-05, Vol.23 (3), p.274-279
• Main Authors: Chandler, Jaime A., van der Woerdt, Alexandra, Prittie, Jennifer E., Chang, Lou
• Format: Article
• Language: English
• Subjects: Animals; complications; corneal injury; corneal ulcer; Dogs; Female; Hospitals, Animal; Intensive Care Units; Male; Reagent Strips; tear film; Tears - physiology
• ISSN: 1479-3261; 1476-4431
• DOI: 10.1111/vec.12055

Objective To determine the tear production in dogs admitted to an intensive care unit (ICU). Design Prospective observational study from November 2010–September 2011. Setting Private emergency and referral hospital. Animals Thirty healthy control dogs and 30 dogs hospitalized in an ICU for treatment of systemic illness without previously diagnosed ophthalmic disorders and no recent history of anesthesia. Enrollment was based on availability of the ophthalmologist within 24 hours of admission to the ICU. Interventions Tear production was measured utilizing Schirmer tear test strips (STT) in healthy control animals as well as in hospitalized canine patients. All patients received an ophthalmic examination by a board‐certified veterinary ophthalmologist within 24 hours of admission to the ICU. Lubrication with artificial tear gel every 2–4 hours as needed was implemented after STT was measured. Measurements and Main Results Average tear productions in the control and canine ICU populations were 24.5 mm/min and 13.2 mm/min, respectively. This was found to be statistically significant (P < 0.001). Furthermore, there was a trend toward a decrease in tear production in patients with kidney disease and a trend toward normal tear production in patients with cardiac disease but the sample size was likely too small to enable detection of a statistically significant difference. Conclusions This study demonstrates a decrease in tear production in canine ICU patients. While further study is warranted to determine how different diseases impact tear production, these finding support the implementation of frequent ocular lubrication in all ICU patients.