Acute Peripheral Arterial Occlusion: Prospective Study Evaluating Intra-Arterial Thrombolysis With a Micro-Porous Balloon Catheter

Purpose To assess the efficacy of a new in situ thrombolysis method using a low-pressure micro-porous balloon catheter (MPBC) compared to a traditional in situ infusion (ISI) of a fibrinolytic agent in the treatment of acute limb ischemia. Methods Between January 2010 and December 2011, 21 patients...

Full description

Saved in:
Bibliographic Details
Published in:Journal of endovascular therapy 2013-06, Vol.20 (3), p.422-426
Main Authors: Bagan, Patrick, Dakhil, Bassel, Lacal, Pierre, Couffinhal, Jean Claude
Format: Article
Language:English
Subjects:
Acute Disease
Adult
Aged
Aged, 80 and over
Arterial Occlusive Diseases - therapy
Blood clots
Catheters
Embolisms
Equipment Design
Female
Heart attacks
Hospitals
Humans
Ischemia
Ischemia - therapy
Leg - blood supply
Male
Middle Aged
Patients
Peripheral Arterial Disease - therapy
Porosity
Prospective Studies
Thrombolytic Therapy - instrumentation
Thrombolytic Therapy - methods
Thrombosis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose To assess the efficacy of a new in situ thrombolysis method using a low-pressure micro-porous balloon catheter (MPBC) compared to a traditional in situ infusion (ISI) of a fibrinolytic agent in the treatment of acute limb ischemia. Methods Between January 2010 and December 2011, 21 patients (14 men; mean age 64.6 years, range 40–92) treated for acute lower limb ischemia were prospectively enrolled in the study. Seven patients underwent in situ thrombolysis using the ISI method and 14 patients the MPBC method to deliver urokinase. The total urokinase dose injected and the length of stay in an intermediate care unit were compared between the groups. Results Recanalization was successful in 90% of cases (6/7 patients in the ISI group; 13/14 patients in the MPBC group). The morbidity was 7% (1 pseudoaneurysm). The dose of urokinase needed was significantly lower (p
ISSN:1526-6028
1545-1550
DOI:10.1583/12-4149MR.1