Effects of field application of the anti-cholinesterase insecticide methomyl on brain acetylcholinesterase activities in wild Mus musculus

The present study was undertaken to measure (AChE) acetylcholinesterase inhibition in small mammals exposed to the carbamate insecticide methomyl, N((methylcarbamoyl) oxy) thioacetimidic acid methyl ester, during agricultural application. Sampling was designed to evaluate temporal effects of methomy...

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Bibliographic Details
Published in:Bulletin of environmental contamination and toxicology 1983-08, Vol.31 (2), p.158-163
Main Authors: Montz, Jr, W E, Scanlon, P F, Kirkpatrick, R L
Format: Article
Language:English
Subjects:
Acetylcholinesterase - metabolism
Animal Population Groups - physiology
Animals
Animals, Wild - physiology
Brain - enzymology
Cholinesterase Inhibitors
Insecticides - toxicity
Methomyl - adverse effects
Methomyl - toxicity
Mice - physiology
Mus musculus
Time Factors
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Summary:The present study was undertaken to measure (AChE) acetylcholinesterase inhibition in small mammals exposed to the carbamate insecticide methomyl, N((methylcarbamoyl) oxy) thioacetimidic acid methyl ester, during agricultural application. Sampling was designed to evaluate temporal effects of methomyl on AChE activity during the first 3 days after spraying because this is the period during which small mammals are most sensitive to AChE inhibitors under laboratory conditions of direct oral dosing.
ISSN:0007-4861
DOI:10.1007/BF01607887