A spectral-domain optical coherence tomography device provides reliable corneal pachymetry measurements in canine eyes

The objective of this study was to determine central corneal thickness (CCT) and the intra- and interuser reliability using a portable spectral-domain optical coherence tomography (SD-OCT) device in canine eyes. Twenty clinically normal dogs were examined. CCT measurements were obtained from both ey...

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Bibliographic Details
Published in:Veterinary record 2013-06, Vol.172 (23), p.605-605
Main Authors: Alario, A. F., Pirie, C. G.
Format: Article
Language:English
Subjects:
Age Factors
Agreements
Animals
Corneal Diseases - diagnosis
Corneal Diseases - veterinary
Corneal Pachymetry - standards
Corneal Pachymetry - veterinary
Data analysis
Dog Diseases - diagnosis
Dogs
Epithelium, Corneal - pathology
Female
Fourier transforms
Humans
Male
Medical imaging
Observer Variation
Quality
Reproducibility of Results
Sex Factors
Software
Statistical analysis
Tomography, Optical Coherence - standards
Tomography, Optical Coherence - veterinary
Veterinary colleges
Veterinary medicine
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Summary:The objective of this study was to determine central corneal thickness (CCT) and the intra- and interuser reliability using a portable spectral-domain optical coherence tomography (SD-OCT) device in canine eyes. Twenty clinically normal dogs were examined. CCT measurements were obtained from both eyes of each animal three times by two operators in succession. The CCT was automatically calculated using the pachymetry software generated from eight radial scans, 6 mm in length. Mean canine CCT was 606.83±39.45 μm for all eyes examined. There was no significant difference in CCT based on the eye examined (OD vs OS), age or gender of the animal. There was no significant difference in CCT between replicates performed by the same operator; however, a small but significant difference was noted in CCT between operators. The mean difference in CCT between operators was 1.9 μm (P=0.03). The coefficient of variation for each user and between users was very low (range 0.64–1.7 per cent). The intraclass correlation coefficient comparing operators was 0.975. Based on these results, the SD-OCT device evaluated is capable of obtaining precise CCT measurements with excellent intra- and interoperator reliability in canine eyes.
ISSN:0042-4900
2042-7670
DOI:10.1136/vr.101530