Serum Levels of the CC Chemokines CCL2, CCL5, and CCL11 in Food Allergic Children with Different Clinical Manifestations

Food allergies (FA) are frequent in 8 % of children under 3 years old and approximately 2 % of adults. Chemokine are involved in various allergies such as FA. The present study was aimed to determine CCL2, CCL5, and CCL11 levels in FA. The study population of this cross-sectional study contained 63...

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Bibliographic Details
Published in:Inflammation 2013-06, Vol.36 (3), p.561-566
Main Authors: Radman, Masood, Hassanshahi, Gholamhossin, Vazirinejad, Reza, Arababadi, Mohammad Kazemi, Karimabad, Mojgan Noorozi, Khorramdelazad, Hossein, Rafatpanah, Houshang, Iranmanesh, Fereshteh, Hakimizadeh, Elham, Ahmadi, Zahra
Format: Article
Language:English
Subjects:
Anaphylaxis - blood
Anaphylaxis - immunology
Asthma - blood
Asthma - immunology
Biomedical and Life Sciences
Biomedicine
Chemokine CCL11 - blood
Chemokine CCL2 - blood
Chemokine CCL5 - blood
Child
Cross-Sectional Studies
Dermatitis, Atopic - blood
Dermatitis, Atopic - immunology
Eosinophils
Female
Food Hypersensitivity - blood
Food Hypersensitivity - immunology
Humans
Immunoglobulin E - blood
Immunology
Internal Medicine
Leukocyte Count
Male
Pathology
Pharmacology/Toxicology
Rheumatology
Urticaria - blood
Urticaria - immunology
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Summary:Food allergies (FA) are frequent in 8 % of children under 3 years old and approximately 2 % of adults. Chemokine are involved in various allergies such as FA. The present study was aimed to determine CCL2, CCL5, and CCL11 levels in FA. The study population of this cross-sectional study contained 63 patients suffering from FA and 100 healthy controls. Concentrations of CCL2, CCL5, CCL11, and IgE were measured by enzyme-linked immunosorbent assay (ELISA). Eosinophils were counted using Casy Ι cell counter + analyzer system model SCAREF system GmbH. Differences were considered significant at P  
ISSN:0360-3997
1573-2576
DOI:10.1007/s10753-012-9577-8