Predictors of Progression of Recently Diagnosed Atrial Fibrillation in REgistry on Cardiac Rhythm DisORDers Assessing the Control of Atrial Fibrillation (RecordAF)–United States Cohort

The progression of atrial fibrillation (AF) to a more sustained form is associated with increased symptoms and morbidity. The aims of the REgistry on Cardiac Rhythm DisORDers Assessing the Control of Atrial Fibrillation (RecordAF)–United States (US) cohort study were to identify the risk factors of...

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Published in:The American journal of cardiology 2013-07, Vol.112 (1), p.79-84
Main Authors: Zhang, Yuan-Yuan, MD, PhD, Qiu, Chunfu, PhD, Davis, Pamela J., MD, Jhaveri, Mehul, PharmD, MPH, Prystowsky, Eric N., MD, Kowey, Peter, MD, Weintraub, William S., MD
Format: Article
Language:English
Subjects:
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Anti-Arrhythmia Agents - therapeutic use
Atrial Fibrillation - drug therapy
Atrial Fibrillation - epidemiology
Atrial Fibrillation - physiopathology
Body mass index
Cardiac arrhythmia
Cardiovascular
Confidence intervals
Disease Progression
Drug therapy
Family medical history
Female
Heart rate
Humans
Logistic Models
Logistics
Male
Patients
Predictive Value of Tests
Propensity Score
Prospective Studies
Registries
Risk Factors
Sinuses
United States - epidemiology
Variables
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Summary:The progression of atrial fibrillation (AF) to a more sustained form is associated with increased symptoms and morbidity. The aims of the REgistry on Cardiac Rhythm DisORDers Assessing the Control of Atrial Fibrillation (RecordAF)–United States (US) cohort study were to identify the risk factors of AF progression and the effects of management approaches. RecordAF is the first worldwide, 1-year observational study of the treatment of community-based patients with recent-onset AF. We assessed AF progression at 12 months in the US cohort. AF progression was defined as a change of AF to a more sustained form (either paroxysmal becoming persistent or permanent, or persistent becoming permanent). The US cohort included 955 patients, with mean age of 68.9 years; 56.8% were men and 88.8% were white. At entry, 59.6% of patients were selected for rate-control and 40.4% for rhythm-control therapy. At 12 months, the management strategy was unchanged for 68.2% of the patients in the rate- and 77.7% of the patients in the rhythm-control groups. Overall, AF progression had occurred in 18.6% of patients at 12 months. The progression rate was significantly greater in the rate-control (27.6%) than in the rhythm-control (5.8%) group (p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2013.02.056