Central nervous system manifestations after pulse therapy for systemic lupus erythematosus

Suchman et al recently suggested a relationship between intravenous methylprednisolone pulse therapy and a seizure in a patient with systemic lupus erythematosus (SLE). The authors have reviewed their experience with using pulse therapy in SLE. Between 1978 and 1982, 18 patients with SLE were treate...

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Bibliographic Details
Published in:Arthritis and rheumatism 1983-06, Vol.26 (6), p.809-810
Main Authors: Ayoub, William T., Torretti, Dennis, Harrington, Thomas M.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Central Nervous System Diseases - chemically induced
Female
Humans
Injections, Intravenous
Lupus Erythematosus, Systemic - drug therapy
Methylprednisolone - administration & dosage
Methylprednisolone - adverse effects
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Summary:Suchman et al recently suggested a relationship between intravenous methylprednisolone pulse therapy and a seizure in a patient with systemic lupus erythematosus (SLE). The authors have reviewed their experience with using pulse therapy in SLE. Between 1978 and 1982, 18 patients with SLE were treated with pulse therapy (1 gm of intravenous methylprednisolone daily for 3 days). Three patients without active central nervous system (CNS) disease developed neurologic manifestations following PT.
ISSN:0004-3591
1529-0131
DOI:10.1002/art.1780260621