Current metabolomics: Practical applications

The field of metabolomics continues to grow rapidly over the last decade and has been proven to be a powerful technology in predicting and explaining complex phenotypes in diverse biological systems. Metabolomics complements other omics, such as transcriptomics and proteomics and since it is a ‘down...

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Bibliographic Details
Published in:Journal of bioscience and bioengineering 2013-06, Vol.115 (6), p.579-589
Main Authors: Putri, Sastia P., Nakayama, Yasumune, Matsuda, Fumio, Uchikata, Takato, Kobayashi, Shizu, Matsubara, Atsuki, Fukusaki, Eiichiro
Format: Article
Language:English
Subjects:
Animals
application
Biological and medical sciences
biology
Biotechnology
Caenorhabditis elegans - metabolism
Chemometrics
Drosophila melanogaster - metabolism
Food plants
Food Technology - trends
Fundamental and applied biological sciences. Psychology
gene expression
genomics
Humans
Mass spectrometry
medicine
Metabolic Diseases - metabolism
Metabolome
Metabolomics
Metabolomics - trends
microbiology
Microbiology - trends
Multivariate analysis
Neoplasms - metabolism
Nervous System Diseases - metabolism
phenotype
Plants - metabolism
prediction
proteomics
synthetic biology
technology
transcriptomics
Zebrafish - metabolism
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Summary:The field of metabolomics continues to grow rapidly over the last decade and has been proven to be a powerful technology in predicting and explaining complex phenotypes in diverse biological systems. Metabolomics complements other omics, such as transcriptomics and proteomics and since it is a ‘downstream’ result of gene expression, changes in the metabolome is considered to best reflect the activities of the cell at a functional level. Thus far, metabolomics might be the sole technology capable of detecting complex, biologically essential changes. As one of the omics technology, metabolomics has exciting applications in varied fields, including medical science, synthetic biology, medicine, and predictive modeling of plant, animal and microbial systems. In addition, integrated applications with genomics, transcriptomics, and proteomics provide greater understanding of global system biology. In this review, we discuss recent applications of metabolomics in microbiology, plant, animal, food, and medical science.
ISSN:1389-1723
1347-4421
DOI:10.1016/j.jbiosc.2012.12.007