Real-time handheld multispectral optoacoustic imaging

Multispectral optoacoustic tomography (MSOT) of functional and molecular contrast has the potential to find broad deployment in clinical practice. We have developed the first handheld MSOT imaging device with fast wavelength tuning achieving a frame rate of 50 Hz. In this Letter, we demonstrate its...

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Bibliographic Details
Published in:Optics letters 2013-05, Vol.38 (9), p.1404-1406
Main Authors: Buehler, Andreas, Kacprowicz, Marcin, Taruttis, Adrian, Ntziachristos, Vasilis
Format: Article
Language:English
Subjects:
Devices
Frames
Hemoglobins - metabolism
Human
Humans
Imaging
Infrared Rays
Oxyhemoglobins - metabolism
Photoacoustic Techniques - instrumentation
Real time
Time Factors
Tomography
Tomography, Optical - instrumentation
Tuning
Wavelengths
Wrist - blood supply
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Summary:Multispectral optoacoustic tomography (MSOT) of functional and molecular contrast has the potential to find broad deployment in clinical practice. We have developed the first handheld MSOT imaging device with fast wavelength tuning achieving a frame rate of 50 Hz. In this Letter, we demonstrate its clinical potential by dynamically resolving multiple disease-relevant tissue chromophores, including oxy-/deoxyhemoglobin, and melanin, in human volunteers.
ISSN:0146-9592
1539-4794
DOI:10.1364/OL.38.001404