Patient Demographics, Quality of Life, and Disease Features of Men With Newly Diagnosed Prostate Cancer: Trends in the PSA Era

• Published in: Urology (Ridgewood, N.J.) N.J.), 2013-07, Vol.82 (1), p.60-66
• Main Authors: Glass, Allison S, Cowan, Janet E, Fuldeore, Mahesh J, Cooperberg, Matthew R, Carroll, Peter R, Kenfield, Stacey A, Greene, Kirsten L
• Format: Article
• Language: English
• Subjects: Adenocarcinoma - complications; Adenocarcinoma - diagnosis; Age Factors; Aged; Biological and medical sciences; Biopsy, Needle - trends; Bone and Bones - diagnostic imaging; Chi-Square Distribution; Gynecology. Andrology. Obstetrics; Humans; Male; Male genital diseases; Medical sciences; Middle Aged; Neoplasm Grading - trends; Nephrology. Urinary tract diseases; Prostate-Specific Antigen - blood; Prostatic Neoplasms - complications; Prostatic Neoplasms - diagnosis; Quality of Life; Radionuclide Imaging - trends; Registries; Sexual Dysfunction, Physiological - etiology; Tomography, X-Ray Computed - trends; Tumors; Tumors of the urinary system; United States; Urinary tract. Prostate gland; Urination Disorders - etiology; Urology
• ISSN: 0090-4295; 1527-9995
• DOI: 10.1016/j.urology.2013.01.072

Objective To describe how demographic and diagnostic characteristics of men with prostate cancer in the United States have changed since 1999, using data from the Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE) registry. Methods The medical records of patients enrolled in CaPSURE between 1999 and 2011 were evaluated. Baseline demographics, disease features, and imaging use were assessed. Mantel-Haenszel chi-square was used to test for trends across diagnostic years. Results Between 1999 and 2011, a total of 9572 patients were diagnosed with prostate cancer and enrolled in CaPSURE at community (36), academic (3), and Veteran's Affairs (4) hospitals. Over the study period, mean age at diagnosis decreased, P