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Malaria vaccine antigen(s): Detergent solubilization, partial isolation, and recovery of immunoprotective activity
Plasmodium berghei-infected erythrocytes were solubilized with nonionic detergent n-octyl glucoside and membrane-containing P. berghei fragments with either n-octyl glucoside or ionic detergent sodium deoxycholate, unsolubilized material was separated by centrifugation and detergent was removed from...
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Published in: | Infection and Immunity 1984, Vol.43 (1), p.442-444 |
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container_title | Infection and Immunity |
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creator | D'Antonio, L.E Keshavarz-Valian, H Alger, N.E |
description | Plasmodium berghei-infected erythrocytes were solubilized with nonionic detergent n-octyl glucoside and membrane-containing P. berghei fragments with either n-octyl glucoside or ionic detergent sodium deoxycholate, unsolubilized material was separated by centrifugation and detergent was removed from respective supernatants by gel filtration, reaggregated components in respective void volume eluates acted as specific vaccine in recipient mice |
doi_str_mv | 10.1128/iai.43.1.442-444.1984 |
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Psychology ; Human protozoal diseases ; immunity ; immunization ; Infectious diseases ; Malaria ; Malaria - immunology ; Malaria - prevention & control ; Medical sciences ; Mice ; Mice, Inbred A ; Parasitic diseases ; Plasmodium berghei ; Plasmodium berghei - pathogenicity ; Protozoa ; Protozoal diseases ; Solubility ; Tropical medicine ; Vaccines</subject><ispartof>Infection and Immunity, 1984, Vol.43 (1), p.442-444</ispartof><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC263461/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC263461/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,3188,3189,4024,27923,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9386059$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6360908$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>D'Antonio, L.E</creatorcontrib><creatorcontrib>Keshavarz-Valian, H</creatorcontrib><creatorcontrib>Alger, N.E</creatorcontrib><title>Malaria vaccine antigen(s): Detergent solubilization, partial isolation, and recovery of immunoprotective activity</title><title>Infection and Immunity</title><addtitle>Infect Immun</addtitle><description>Plasmodium berghei-infected erythrocytes were solubilized with nonionic detergent n-octyl glucoside and membrane-containing P. berghei fragments with either n-octyl glucoside or ionic detergent sodium deoxycholate, unsolubilized material was separated by centrifugation and detergent was removed from respective supernatants by gel filtration, reaggregated components in respective void volume eluates acted as specific vaccine in recipient mice</description><subject>Animals</subject><subject>antigens</subject><subject>Antigens, Surface - immunology</subject><subject>Antigens, Surface - isolation & purification</subject><subject>Biochemistry. Physiology. Immunology. Molecular biology</subject><subject>Biological and medical sciences</subject><subject>Detergents</subject><subject>Erythrocytes - physiology</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Human protozoal diseases</subject><subject>immunity</subject><subject>immunization</subject><subject>Infectious diseases</subject><subject>Malaria</subject><subject>Malaria - immunology</subject><subject>Malaria - prevention & control</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Mice, Inbred A</subject><subject>Parasitic diseases</subject><subject>Plasmodium berghei</subject><subject>Plasmodium berghei - pathogenicity</subject><subject>Protozoa</subject><subject>Protozoal diseases</subject><subject>Solubility</subject><subject>Tropical medicine</subject><subject>Vaccines</subject><issn>0019-9567</issn><issn>1098-5522</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><recordid>eNqFkV2LEzEUhoMoa7f6ExbnQkTBGfPdRPBC1k9Y8UL3OpxJM21kZlKTTKX7603pUNwrL8Lh5H3OmxxehK4Ibgih6o0H33DWkIZzWnPOG6IVf4AWBGtVC0HpQ7TAmOhaC7l6jC5T-lXaAqoLdCGZxBqrBYrfoIfoodqDtX50FYzZb9z4Mr16W31w2cXS5CqFfmp97-8g-zC-rnYQs4e-8kWYr2BcV9HZsHfxUIWu8sMwjWEXQ3Y2-31xPhafD0_Qow765J7OdYluP338ef2lvvn--ev1-5vacklzzYUVorOdZRR3du2kcK1tKdUdxy13igvtGHOg5VoqS8QKympKgLTOKkVatkTvTr67qR3c2pY9IvRmF_0A8WACeHNfGf3WbMLeUMm4JGX-xTwfw-_JpWwGn6zrexhdmJJRWDMq1f9BwlZcrYrrEokTaGNIKbru_BmCzTFUU0I1nBliSqjlcHMMtcxd_bvJeWpOsejPZx2Shb6LMFqfzphmSmKhC1adsK3fbP_46Ayk4d6TBXl2QjoIBjaxuNz-oJgwTCnmK8LYXw60wvs</recordid><startdate>1984</startdate><enddate>1984</enddate><creator>D'Antonio, L.E</creator><creator>Keshavarz-Valian, H</creator><creator>Alger, N.E</creator><general>American Society for Microbiology</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7T5</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>1984</creationdate><title>Malaria vaccine antigen(s): Detergent solubilization, partial isolation, and recovery of immunoprotective activity</title><author>D'Antonio, L.E ; Keshavarz-Valian, H ; Alger, N.E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c462t-45c55fcfc320fcde65ebcb229f40b4e8459e33ea96d68c157a44885a6cec881b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Animals</topic><topic>antigens</topic><topic>Antigens, Surface - immunology</topic><topic>Antigens, Surface - isolation & purification</topic><topic>Biochemistry. Physiology. Immunology. Molecular biology</topic><topic>Biological and medical sciences</topic><topic>Detergents</topic><topic>Erythrocytes - physiology</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Human protozoal diseases</topic><topic>immunity</topic><topic>immunization</topic><topic>Infectious diseases</topic><topic>Malaria</topic><topic>Malaria - immunology</topic><topic>Malaria - prevention & control</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Mice, Inbred A</topic><topic>Parasitic diseases</topic><topic>Plasmodium berghei</topic><topic>Plasmodium berghei - pathogenicity</topic><topic>Protozoa</topic><topic>Protozoal diseases</topic><topic>Solubility</topic><topic>Tropical medicine</topic><topic>Vaccines</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>D'Antonio, L.E</creatorcontrib><creatorcontrib>Keshavarz-Valian, H</creatorcontrib><creatorcontrib>Alger, N.E</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Infection and Immunity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>D'Antonio, L.E</au><au>Keshavarz-Valian, H</au><au>Alger, N.E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Malaria vaccine antigen(s): Detergent solubilization, partial isolation, and recovery of immunoprotective activity</atitle><jtitle>Infection and Immunity</jtitle><addtitle>Infect Immun</addtitle><date>1984</date><risdate>1984</risdate><volume>43</volume><issue>1</issue><spage>442</spage><epage>444</epage><pages>442-444</pages><issn>0019-9567</issn><eissn>1098-5522</eissn><coden>INFIBR</coden><abstract>Plasmodium berghei-infected erythrocytes were solubilized with nonionic detergent n-octyl glucoside and membrane-containing P. berghei fragments with either n-octyl glucoside or ionic detergent sodium deoxycholate, unsolubilized material was separated by centrifugation and detergent was removed from respective supernatants by gel filtration, reaggregated components in respective void volume eluates acted as specific vaccine in recipient mice</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>6360908</pmid><doi>10.1128/iai.43.1.442-444.1984</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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source | Open Access: PubMed Central; American Society for Microbiology Journals |
subjects | Animals antigens Antigens, Surface - immunology Antigens, Surface - isolation & purification Biochemistry. Physiology. Immunology. Molecular biology Biological and medical sciences Detergents Erythrocytes - physiology Female Fundamental and applied biological sciences. Psychology Human protozoal diseases immunity immunization Infectious diseases Malaria Malaria - immunology Malaria - prevention & control Medical sciences Mice Mice, Inbred A Parasitic diseases Plasmodium berghei Plasmodium berghei - pathogenicity Protozoa Protozoal diseases Solubility Tropical medicine Vaccines |
title | Malaria vaccine antigen(s): Detergent solubilization, partial isolation, and recovery of immunoprotective activity |
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