Antibacterial activity of local herbs collected from Murree (Pakistan) against multi-drug resistant Klebsiella pneumonae, E. coli and methyciline resistant Staphylococcus aureus

Exploring healing power in plants emerged in prehistory of human civilization. Sustaining good health has been achieved over the millions of years by use of plant products in various traditional sockets. A major contribution of medicinal plants to health care systems is their limitless possession of...

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Bibliographic Details
Published in:Pakistan journal of pharmaceutical sciences 2013-07, Vol.26 (4), p.827-830
Main Authors: Mansoor, Qaisar, Shaheen, Saira, Javed, Uzma, Shaheen, Uzma, Iqrar, Irum, Ismail, Muhammad
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
Bacterial infections
Care and treatment
Drug Resistance, Multiple, Bacterial
Escherichia coli - drug effects
Health aspects
Humans
Klebsiella pneumoniae - drug effects
Medicine, Botanic
Medicine, Herbal
Methicillin-Resistant Staphylococcus aureus - drug effects
Pakistan
Plant Extracts - pharmacology
Plants, Medicinal
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Summary:Exploring healing power in plants emerged in prehistory of human civilization. Sustaining good health has been achieved over the millions of years by use of plant products in various traditional sockets. A major contribution of medicinal plants to health care systems is their limitless possession of bioactive components that stimulate explicit physiological actions. Luckily Pakistan is blessed with huge reservoir of plants with medicinal potential and some of them; we focused in this study for their medicinal importance.In this study we checked the antibacterial activity inherent in Ricinus communis, Solanum nigrum, Dodonaea viscose and Berberis lyceum extracts for multidrug resistance bacterial strains Klebsiella pneumonae, E. coli and methyciline resistant Staphylococcus aureus. MRSA showed sensitivity for Ricinus communis. Multidrug resistant Klebsiella pneumonae was sensitive with Pine roxburgii and Ricinus communis but weakly susceptible for Solanum nigrum. Multidrug resistant E. coli was resistant to all plant extracts. Treatment of severe infections caused by the bacterial strains used in this study with Ricinus communis, Pine roxburgii and Solanum nigrum can lower the undesired side effects of synthetic medicine and also reduce the economic burden.
ISSN:1011-601X